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- W1502777848 abstract "This chapter discusses the cellular dynamics in invertebrate neurosecretory systems. The chromatographic and electrophoretic microtechniques provide complete information on the range of active factors and their distribution in individual species. Assays of synthetic crustacean chromatophorotropins tend to confirm the impression derived from many partial purification schemes that unique molecules have the potential to affect several target organs. It is likely, however, that organisms possess mechanisms to control separately the responsiveness of individual targets. Such mechanisms might include: local control of target sensitivity mediated through some aspect of the intrinsic metabolism of a particular target; the antagonistic or synergistic control of some targets of a particular hormone by blood-borne factors from other sources, or by nervous input; local differences in hormone concentration occasioned by direct delivery of a hormone to some tissues and broadcast dispersal through the circulatory system to others. Studies on mollusc neurosecretory cells have demonstrated clearly that several peptides are released by the activation of a homogeneous population of neurosecretory cells. The techniques of electron microscope autoradiography have been used only sparingly in studies of invertebrate neurosecretory systems and have the potential to provide valuable information on granule processing and transport, and on the possibility of an extragranular pool of hormone or hormone-associated molecules in the axon terminals. Some invertebrate neurosecretory cells present many of the same experimental advantages for electrophysiological studies as ordinary invertebrate neurons over their counterparts in vertebrates." @default.
- W1502777848 created "2016-06-24" @default.
- W1502777848 creator A5048680151 @default.
- W1502777848 date "1977-01-01" @default.
- W1502777848 modified "2023-09-23" @default.
- W1502777848 title "Cellular Dynamics in Invertebrate Neurosecretory Systems" @default.
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