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- W1502808889 abstract "Aim. The main factors of cardiovascular risk, particularly hypercholesterolemia, in patients with coronary heart disease are considered, comparative characteristic of the statins efficiency is given, and factors that determine the effectiveness of intolerance and lack of a standard hypocholesterolemia therapy are described. From the point of view of genetics is considered a promising direction of research on the development of monoclonal antibodies to the proprotein convertase subtilisin / kexin type 9, and their effect on the lipid profile in patients at high risk.Conclusions. Statins are the main agents in the treatment and prevention of coronary heart disease. PCSK9 is an important regulator of LDL cholesterol through the effect on LDL receptors. Blocking the PCSK9 is a new mechanism in reducing LDL cholesterol" @default.
- W1502808889 created "2016-06-24" @default.
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- W1502808889 date "2015-03-19" @default.
- W1502808889 modified "2023-10-17" @default.
- W1502808889 title "Modern strategy of treatment hypercholesterolemia" @default.
- W1502808889 doi "https://doi.org/10.15587/2313-8416.2015.39266" @default.
- W1502808889 hasPublicationYear "2015" @default.
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