FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1502985427> ?p ?o ?g. }

• W1502985427 endingPage "610" @default.
• W1502985427 startingPage "601" @default.
• W1502985427 abstract "What has been learned about electronic health data as a primary data source for regulatory decisions regarding the harms of drugs? Observational studies with electronic health data for postmarket risk assessment can now be conducted in Europe and the US in patient populations numbering in the tens of millions compared with a few hundred patients in a typical clinical trial. With standard protocols, results can be obtained in a few months; however, extensive research published by scores of investigators has illuminated the many obstacles that prevent obtaining robust, reproducible results that are reliable enough to be a primary source for drug safety decisions involving the health and safety of millions of patients. The most widely used terminology for coding patient interactions with medical providers for payment has proved ill-suited to identifying the adverse effects of drugs. Directly conflicting results were reported in otherwise similar patient health databases, even using identical event definitions and research methods. Evaluation of some accepted statistical methods revealed systematic bias, while others appeared to be unreliable. When electronic health data studies detected no drug risk, there were no robust and accepted standards to judge whether the drug was unlikely to cause the adverse effect or whether the study was incapable of detecting it. Substantial investment and careful thinking is needed to improve the reliability of risk assessments based on electronic health data, and current limitations need to be fully understood." @default.
• W1502985427 created "2016-06-24" @default.
• W1502985427 creator A5052645655 @default.
• W1502985427 creator A5053278328 @default.
• W1502985427 date "2015-05-30" @default.
• W1502985427 modified "2023-10-16" @default.
• W1502985427 title "Electronic Health Data for Postmarket Surveillance: A Vision Not Realized" @default.
• W1502985427 cites W1484976590 @default.
• W1502985427 cites W1554437664 @default.
• W1502985427 cites W1732871190 @default.
• W1502985427 cites W1868446464 @default.
• W1502985427 cites W1977447213 @default.
• W1502985427 cites W1989378925 @default.
• W1502985427 cites W2002602253 @default.
• W1502985427 cites W2004257208 @default.
• W1502985427 cites W2015929254 @default.
• W1502985427 cites W2034329819 @default.
• W1502985427 cites W2034536527 @default.
• W1502985427 cites W2048576379 @default.
• W1502985427 cites W2054315914 @default.
• W1502985427 cites W2061013168 @default.
• W1502985427 cites W2062417462 @default.
• W1502985427 cites W2063976695 @default.
• W1502985427 cites W2087467131 @default.
• W1502985427 cites W2087836606 @default.
• W1502985427 cites W2088263677 @default.
• W1502985427 cites W2093717635 @default.
• W1502985427 cites W2102443193 @default.
• W1502985427 cites W2106188657 @default.
• W1502985427 cites W2131801584 @default.
• W1502985427 cites W2138777362 @default.
• W1502985427 cites W2142807897 @default.
• W1502985427 cites W2143684620 @default.
• W1502985427 cites W2149676192 @default.
• W1502985427 cites W2152199962 @default.
• W1502985427 cites W2314496365 @default.
• W1502985427 doi "https://doi.org/10.1007/s40264-015-0305-9" @default.
• W1502985427 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26025018" @default.
• W1502985427 hasPublicationYear "2015" @default.
• W1502985427 type Work @default.
• W1502985427 sameAs 1502985427 @default.
• W1502985427 citedByCount "33" @default.
• W1502985427 countsByYear W15029854272015 @default.
• W1502985427 countsByYear W15029854272016 @default.
• W1502985427 countsByYear W15029854272017 @default.
• W1502985427 countsByYear W15029854272018 @default.
• W1502985427 countsByYear W15029854272019 @default.
• W1502985427 countsByYear W15029854272020 @default.
• W1502985427 countsByYear W15029854272021 @default.
• W1502985427 countsByYear W15029854272022 @default.
• W1502985427 countsByYear W15029854272023 @default.
• W1502985427 crossrefType "journal-article" @default.
• W1502985427 hasAuthorship W1502985427A5052645655 @default.
• W1502985427 hasAuthorship W1502985427A5053278328 @default.
• W1502985427 hasBestOaLocation W15029854271 @default.
• W1502985427 hasConcept C112930515 @default.
• W1502985427 hasConcept C138885662 @default.
• W1502985427 hasConcept C142724271 @default.
• W1502985427 hasConcept C144133560 @default.
• W1502985427 hasConcept C162118730 @default.
• W1502985427 hasConcept C17744445 @default.
• W1502985427 hasConcept C197934379 @default.
• W1502985427 hasConcept C199539241 @default.
• W1502985427 hasConcept C23131810 @default.
• W1502985427 hasConcept C2779473830 @default.
• W1502985427 hasConcept C41895202 @default.
• W1502985427 hasConcept C535046627 @default.
• W1502985427 hasConcept C545542383 @default.
• W1502985427 hasConcept C547195049 @default.
• W1502985427 hasConcept C71924100 @default.
• W1502985427 hasConcept C98274493 @default.
• W1502985427 hasConceptScore W1502985427C112930515 @default.
• W1502985427 hasConceptScore W1502985427C138885662 @default.
• W1502985427 hasConceptScore W1502985427C142724271 @default.
• W1502985427 hasConceptScore W1502985427C144133560 @default.
• W1502985427 hasConceptScore W1502985427C162118730 @default.
• W1502985427 hasConceptScore W1502985427C17744445 @default.
• W1502985427 hasConceptScore W1502985427C197934379 @default.
• W1502985427 hasConceptScore W1502985427C199539241 @default.
• W1502985427 hasConceptScore W1502985427C23131810 @default.
• W1502985427 hasConceptScore W1502985427C2779473830 @default.
• W1502985427 hasConceptScore W1502985427C41895202 @default.
• W1502985427 hasConceptScore W1502985427C535046627 @default.
• W1502985427 hasConceptScore W1502985427C545542383 @default.
• W1502985427 hasConceptScore W1502985427C547195049 @default.
• W1502985427 hasConceptScore W1502985427C71924100 @default.
• W1502985427 hasConceptScore W1502985427C98274493 @default.
• W1502985427 hasIssue "7" @default.
• W1502985427 hasLocation W15029854271 @default.
• W1502985427 hasLocation W15029854272 @default.
• W1502985427 hasOpenAccess W1502985427 @default.
• W1502985427 hasPrimaryLocation W15029854271 @default.
• W1502985427 hasRelatedWork W1969477129 @default.
• W1502985427 hasRelatedWork W2131808775 @default.
• W1502985427 hasRelatedWork W2350593162 @default.
• W1502985427 hasRelatedWork W2353483812 @default.
• W1502985427 hasRelatedWork W2359533638 @default.
• W1502985427 hasRelatedWork W2360756181 @default.

• next