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- W1503000610 abstract "Background: The current guidelines recommend combination therapy of antibiotics empirically for pneumonia patients with risks of PDR pathogens. However, this recommendation remains controversial. [Aims and objectives] To elucidate factors which may lead physicians to select combination therapy of antibiotics for pneumonia. Materials: Pneumonia patients who were admitted to National Center for Geriatrics and Gerontology Hospital from April 2008 to December 2009, and treated with carbapenem (A group, n=70) or combination of carbapenem+aminoglycosides (B group, n=68). Methods: Information on age, gender, weight, risk factors of PDR pathogens, pneumonia type (CAP/HCAP/HAP), Barthel index, clinical response, duration of therapy and 30-day mortality were obtained from chart review. We compared the aforementioned factors between two groups using multiple logistic regression analysis. Results: There were significant differences about the aforementioned factors except age between A and B group in univariate analysis. However, in multivariate logistic regression analysis, only Barthel index was significantly different between both groups (81.8±29.2 in A group vs. 59.1±40.3 in B group, P P =0.067). Duration of antibiotics therapy was significantly shorter in A group compared with B group (7.3±4.7 vs. 19.3±8.2 days, respectively, P Conclusion: Barthel index was the independent factor which affected physicians to select combination therapy of antibiotics." @default.
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- W1503000610 date "2011-09-01" @default.
- W1503000610 modified "2023-09-23" @default.
- W1503000610 title "Difference of patient background with pneumonia between monotherapy and combination" @default.
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