FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1503389976> ?p ?o ?g. }

• W1503389976 endingPage "2911" @default.
• W1503389976 startingPage "2907" @default.
• W1503389976 abstract "Human adenovirus E1A proteins can repress the expression of several viral and cellular genes. By using a cell-free transcription system, we demonstrated that the gene product of the E1A 12S mRNA, the 243-residue protein E1A243R, inhibits basal transcription from the human immunodeficiency virus type 1 (HIV-1) long terminal repeat (LTR). The HIV-1 transactivator protein Tat greatly stimulates transcription from the viral promoter in vitro. However, E1A243R can repress Tat-activated transcription in vitro. Strong repression of both basal and Tat-activated transcriptions requires only E1A N-terminal amino acid residues 1 to 80. Deletion analysis showed that E1A N-terminal amino acids 4 to 25 are essential for repression, whereas amino acid residues 30 to 49 and 70 to 80 are dispensable. Transcriptional repression by E1A in the cell-free transcription system is promoter specific, since under identical conditions, transcription of the adenovirus major late promoter and the Rous sarcoma virus LTR promoter was unaffected. The repression of transcription by small E1A peptides in vitro provides an assay for investigation of molecular mechanisms governing E1A-mediated repression of both basal and Tat-activated transcriptions of the HIV-1 LTR promoter." @default.
• W1503389976 created "2016-06-24" @default.
• W1503389976 creator A5029644738 @default.
• W1503389976 creator A5045312852 @default.
• W1503389976 creator A5049015016 @default.
• W1503389976 date "1995-05-01" @default.
• W1503389976 modified "2023-10-16" @default.
• W1503389976 title "Repression in vitro, by human adenovirus E1A protein domains, of basal or Tat-activated transcription of the human immunodeficiency virus type 1 long terminal repeat" @default.
• W1503389976 cites W1542161618 @default.
• W1503389976 cites W1792129397 @default.
• W1503389976 cites W1893246485 @default.
• W1503389976 cites W1911649157 @default.
• W1503389976 cites W1957161932 @default.
• W1503389976 cites W1966063731 @default.
• W1503389976 cites W1967404701 @default.
• W1503389976 cites W1968873679 @default.
• W1503389976 cites W1971436037 @default.
• W1503389976 cites W1973174225 @default.
• W1503389976 cites W1977282539 @default.
• W1503389976 cites W1986943051 @default.
• W1503389976 cites W1991670386 @default.
• W1503389976 cites W2006979668 @default.
• W1503389976 cites W2010416554 @default.
• W1503389976 cites W2014387209 @default.
• W1503389976 cites W2028706937 @default.
• W1503389976 cites W2031583162 @default.
• W1503389976 cites W2033529039 @default.
• W1503389976 cites W2035516686 @default.
• W1503389976 cites W2040003193 @default.
• W1503389976 cites W2042134050 @default.
• W1503389976 cites W2048671183 @default.
• W1503389976 cites W2055490337 @default.
• W1503389976 cites W2058609274 @default.
• W1503389976 cites W2063798194 @default.
• W1503389976 cites W2065688863 @default.
• W1503389976 cites W2074159737 @default.
• W1503389976 cites W2080835064 @default.
• W1503389976 cites W2082702373 @default.
• W1503389976 cites W2086161207 @default.
• W1503389976 cites W2089241243 @default.
• W1503389976 cites W2090084965 @default.
• W1503389976 cites W2093428365 @default.
• W1503389976 cites W2132269792 @default.
• W1503389976 cites W2145312783 @default.
• W1503389976 cites W2151920048 @default.
• W1503389976 cites W2163757819 @default.
• W1503389976 cites W2180476901 @default.
• W1503389976 cites W2395612267 @default.
• W1503389976 cites W2413499592 @default.
• W1503389976 cites W2417830359 @default.
• W1503389976 cites W2418747844 @default.
• W1503389976 doi "https://doi.org/10.1128/jvi.69.5.2907-2911.1995" @default.
• W1503389976 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/188988" @default.
• W1503389976 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7707515" @default.
• W1503389976 hasPublicationYear "1995" @default.
• W1503389976 type Work @default.
• W1503389976 sameAs 1503389976 @default.
• W1503389976 citedByCount "19" @default.
• W1503389976 countsByYear W15033899762012 @default.
• W1503389976 countsByYear W15033899762016 @default.
• W1503389976 countsByYear W15033899762017 @default.
• W1503389976 countsByYear W15033899762018 @default.
• W1503389976 crossrefType "journal-article" @default.
• W1503389976 hasAuthorship W1503389976A5029644738 @default.
• W1503389976 hasAuthorship W1503389976A5045312852 @default.
• W1503389976 hasAuthorship W1503389976A5049015016 @default.
• W1503389976 hasBestOaLocation W15033899761 @default.
• W1503389976 hasConcept C101762097 @default.
• W1503389976 hasConcept C104317684 @default.
• W1503389976 hasConcept C1292079 @default.
• W1503389976 hasConcept C138885662 @default.
• W1503389976 hasConcept C144825837 @default.
• W1503389976 hasConcept C150194340 @default.
• W1503389976 hasConcept C153911025 @default.
• W1503389976 hasConcept C159047783 @default.
• W1503389976 hasConcept C179926584 @default.
• W1503389976 hasConcept C186310378 @default.
• W1503389976 hasConcept C199491388 @default.
• W1503389976 hasConcept C2522874641 @default.
• W1503389976 hasConcept C2777441520 @default.
• W1503389976 hasConcept C2910020833 @default.
• W1503389976 hasConcept C41895202 @default.
• W1503389976 hasConcept C54355233 @default.
• W1503389976 hasConcept C86339819 @default.
• W1503389976 hasConcept C86803240 @default.
• W1503389976 hasConceptScore W1503389976C101762097 @default.
• W1503389976 hasConceptScore W1503389976C104317684 @default.
• W1503389976 hasConceptScore W1503389976C1292079 @default.
• W1503389976 hasConceptScore W1503389976C138885662 @default.
• W1503389976 hasConceptScore W1503389976C144825837 @default.
• W1503389976 hasConceptScore W1503389976C150194340 @default.
• W1503389976 hasConceptScore W1503389976C153911025 @default.
• W1503389976 hasConceptScore W1503389976C159047783 @default.
• W1503389976 hasConceptScore W1503389976C179926584 @default.
• W1503389976 hasConceptScore W1503389976C186310378 @default.
• W1503389976 hasConceptScore W1503389976C199491388 @default.
• W1503389976 hasConceptScore W1503389976C2522874641 @default.
• W1503389976 hasConceptScore W1503389976C2777441520 @default.

• next