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- W1503424764 abstract "The visual system has often been thought of as a parallel processor because distinct regions of the brain process different features of visual information. However, increasing evidence for convergence and divergence of circuit connections, even at the level of the retina where visual information is first processed, chips away at a model of dedicated and distinct pathways for parallel information flow. Instead, our current understanding is that parallel channels may emerge, not from exclusive microcircuits for each channel, but from unique combinations of microcircuits. This review depicts diagrammatically the current knowledge and remaining puzzles about the retinal circuit with a focus on the mouse retina. Advances in techniques for labelling cells and genetic manipulations have popularized the use of transgenic mice. We summarize evidence gained from serial electron microscopy, electrophysiology and light microscopy to illustrate the wiring patterns in mouse retina. We emphasize the need to explore proposed retinal connectivity using multiple methods to verify circuits both structurally and functionally." @default.
- W1503424764 created "2016-06-24" @default.
- W1503424764 creator A5057642391 @default.
- W1503424764 creator A5063276804 @default.
- W1503424764 date "2014-09-29" @default.
- W1503424764 modified "2023-10-17" @default.
- W1503424764 title "Wiring patterns in the mouse retina: collecting evidence across the connectome, physiology and light microscopy" @default.
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- W1503424764 doi "https://doi.org/10.1113/jphysiol.2014.277228" @default.
- W1503424764 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4259528" @default.
- W1503424764 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25172948" @default.
- W1503424764 hasPublicationYear "2014" @default.
- W1503424764 type Work @default.