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- W1503425512 abstract "Follow-up information has been obtained regarding nineteen families of propositi with overt gout, originally studied in 1938–1946. During 1961–1962 it was possible to examine all nine surviving propositi and sixty-nine of the surviving eighty relatives, as well as 193 relatives who were studied for the first time. The results are similar to those of previous investigations in suggesting that the prevalence of gout and asymptomatic hyperuricemia is increased among the relatives of gouty patients. They are further in accordance with the accepted belief that in male subjects hyperuricemia tends to manifest itself after adolescence, whereas in female subjects it does not do so until after the menopause. They also suggest that hyperuricemia, in those relatives who once manifest it, tends to persist as a fixed trait subjecting the individual to an increased risk of developing overt gout." @default.
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- W1503425512 date "1964-12-01" @default.
- W1503425512 modified "2023-09-27" @default.
- W1503425512 title "Observations on the natural history of hyperuricemia and gout" @default.
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- W1503425512 doi "https://doi.org/10.1016/0002-9343(64)90129-9" @default.
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