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- W1503668094 abstract "Abstract : Hydroxylammonium nitrate (HAN), a major component of the liquid propellant 1846 (LP1846), has been reported to produce methemoglobinemia, Heinz body formation, and hypotension in rats. This study was conducted to define the relative sensitivity and reversibility of the methemoglobinemia, hypotension, and Heinz body formation following oral administration of LP1846 to male rats. Blood pressure was monitored before dosing and for 60 minutes following dosing. Blood samples for determining the presence of methemoglobin and identifying Heinz bodies were obtained at intervals until methemoglobin values returned to normal. Heinz bodies were present in all treated animals. These data suggest that the presence of elevated methemoglobin levels and/or Heinz bodies would be useful indices of occupational exposure to LP1846." @default.
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- W1503668094 date "1988-06-01" @default.
- W1503668094 modified "2023-09-24" @default.
- W1503668094 title "Circulatory and Hematological Effects of Liquid Propellant 1846 Following Oral Administration to Rats" @default.
- W1503668094 doi "https://doi.org/10.21236/ada198046" @default.
- W1503668094 hasPublicationYear "1988" @default.
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