FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1503668654> ?p ?o ?g. }

• W1503668654 endingPage "92" @default.
• W1503668654 startingPage "86" @default.
• W1503668654 abstract "To report on the efficacy, safety, and tolerability of sertraline in the treatment of elderly depres-sed patients with and without comorbid medical illness.Multicenter.Randomized, double-blind, placebo-controlled study.A total of 752 patients aged 60 and older with diagnosis of major depressive disorder according to Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, diagnosis.Outcome measures included the 17-item Hamilton Depression Scale (HAMD); the Clinical Global Depression-Severity/Improvement (CGI-S/CGI-I); efficacy and safety/adverse event assessments; Quality of Life, Enjoyment, and Satisfaction Questionnaire; and the Medical Outcomes Study 36-Item Short-Form Health Status Survey.In the overall sample, sertraline was superior to placebo on all three primary outcome measures, HAMD, and overall clinical severity and change (CGI-S/CGI-I). Furthermore, therapeutic response to sertraline was comparable in those with or without medical comorbidity, and there were no treatment-by-comorbidity group interactions. Sertraline was also associated with a faster time to response than placebo in the comorbid group (P<.006). Sertraline-treated patients in the comorbid group had similar adverse events and discontinuations when compared to those in the noncomorbid group.Sertraline was efficacious in reducing depressive symptomatology, regardless of the presence of comorbid medical illness. Sertraline was safe and well tolerated by patients with or without medical illness." @default.
• W1503668654 created "2016-06-24" @default.
• W1503668654 creator A5005056000 @default.
• W1503668654 creator A5005402511 @default.
• W1503668654 creator A5026913339 @default.
• W1503668654 creator A5045843215 @default.
• W1503668654 creator A5048939577 @default.
• W1503668654 creator A5056798976 @default.
• W1503668654 creator A5058548310 @default.
• W1503668654 creator A5059316770 @default.
• W1503668654 creator A5090774179 @default.
• W1503668654 date "2003-12-24" @default.
• W1503668654 modified "2023-10-13" @default.
• W1503668654 title "Efficacy, Safety, and Tolerability of Sertraline in Patients with Late-Life Depression and Comorbid Medical Illness" @default.
• W1503668654 cites W1849374747 @default.
• W1503668654 cites W1964372552 @default.
• W1503668654 cites W1973485052 @default.
• W1503668654 cites W1977250577 @default.
• W1503668654 cites W1987584662 @default.
• W1503668654 cites W2014745524 @default.
• W1503668654 cites W2027902302 @default.
• W1503668654 cites W2031146523 @default.
• W1503668654 cites W2031408498 @default.
• W1503668654 cites W2055080279 @default.
• W1503668654 cites W2056065496 @default.
• W1503668654 cites W2073185943 @default.
• W1503668654 cites W2088480310 @default.
• W1503668654 cites W2102445568 @default.
• W1503668654 cites W2106503056 @default.
• W1503668654 cites W2113929941 @default.
• W1503668654 cites W2156139207 @default.
• W1503668654 cites W2160070901 @default.
• W1503668654 cites W2160504971 @default.
• W1503668654 doi "https://doi.org/10.1111/j.1532-5415.2004.52015.x" @default.
• W1503668654 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14687320" @default.
• W1503668654 hasPublicationYear "2003" @default.
• W1503668654 type Work @default.
• W1503668654 sameAs 1503668654 @default.
• W1503668654 citedByCount "82" @default.
• W1503668654 countsByYear W15036686542012 @default.
• W1503668654 countsByYear W15036686542013 @default.
• W1503668654 countsByYear W15036686542014 @default.
• W1503668654 countsByYear W15036686542015 @default.
• W1503668654 countsByYear W15036686542016 @default.
• W1503668654 countsByYear W15036686542017 @default.
• W1503668654 countsByYear W15036686542018 @default.
• W1503668654 countsByYear W15036686542019 @default.
• W1503668654 countsByYear W15036686542020 @default.
• W1503668654 countsByYear W15036686542021 @default.
• W1503668654 countsByYear W15036686542022 @default.
• W1503668654 countsByYear W15036686542023 @default.
• W1503668654 crossrefType "journal-article" @default.
• W1503668654 hasAuthorship W1503668654A5005056000 @default.
• W1503668654 hasAuthorship W1503668654A5005402511 @default.
• W1503668654 hasAuthorship W1503668654A5026913339 @default.
• W1503668654 hasAuthorship W1503668654A5045843215 @default.
• W1503668654 hasAuthorship W1503668654A5048939577 @default.
• W1503668654 hasAuthorship W1503668654A5056798976 @default.
• W1503668654 hasAuthorship W1503668654A5058548310 @default.
• W1503668654 hasAuthorship W1503668654A5059316770 @default.
• W1503668654 hasAuthorship W1503668654A5090774179 @default.
• W1503668654 hasConcept C118552586 @default.
• W1503668654 hasConcept C126322002 @default.
• W1503668654 hasConcept C139719470 @default.
• W1503668654 hasConcept C142724271 @default.
• W1503668654 hasConcept C162324750 @default.
• W1503668654 hasConcept C168563851 @default.
• W1503668654 hasConcept C197934379 @default.
• W1503668654 hasConcept C204787440 @default.
• W1503668654 hasConcept C27081682 @default.
• W1503668654 hasConcept C2776867660 @default.
• W1503668654 hasConcept C2777198177 @default.
• W1503668654 hasConcept C2777669559 @default.
• W1503668654 hasConcept C2778375690 @default.
• W1503668654 hasConcept C2779159551 @default.
• W1503668654 hasConcept C2779177272 @default.
• W1503668654 hasConcept C2780051608 @default.
• W1503668654 hasConcept C2780733359 @default.
• W1503668654 hasConcept C535046627 @default.
• W1503668654 hasConcept C558461103 @default.
• W1503668654 hasConcept C71924100 @default.
• W1503668654 hasConceptScore W1503668654C118552586 @default.
• W1503668654 hasConceptScore W1503668654C126322002 @default.
• W1503668654 hasConceptScore W1503668654C139719470 @default.
• W1503668654 hasConceptScore W1503668654C142724271 @default.
• W1503668654 hasConceptScore W1503668654C162324750 @default.
• W1503668654 hasConceptScore W1503668654C168563851 @default.
• W1503668654 hasConceptScore W1503668654C197934379 @default.
• W1503668654 hasConceptScore W1503668654C204787440 @default.
• W1503668654 hasConceptScore W1503668654C27081682 @default.
• W1503668654 hasConceptScore W1503668654C2776867660 @default.
• W1503668654 hasConceptScore W1503668654C2777198177 @default.
• W1503668654 hasConceptScore W1503668654C2777669559 @default.
• W1503668654 hasConceptScore W1503668654C2778375690 @default.
• W1503668654 hasConceptScore W1503668654C2779159551 @default.
• W1503668654 hasConceptScore W1503668654C2779177272 @default.
• W1503668654 hasConceptScore W1503668654C2780051608 @default.
• W1503668654 hasConceptScore W1503668654C2780733359 @default.

• next