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- W1503816963 abstract "Abstract Leukemia cells from a patient with chronic lymphocytic leukemia (CLL) were found to bind sheep RBC (SRBC) through their monoclonal surface IgM. A lymphoblastoid cell line was obtained by immortalization of leukemic cells with Epstein-Barr virus (EBV). Cultured leukemic cells were found to have a supernumerary chromosome 12, an abnormality typical of CLL of the B cell type. To our knowledge, this is the first EBV-immortalized cell line from B-CLL cells of known SRBC specificity and the third reported CLL cell line carrying trisomy of chromosome 12." @default.
- W1503816963 created "2016-06-24" @default.
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- W1503816963 date "1988-01-01" @default.
- W1503816963 modified "2023-09-27" @default.
- W1503816963 title "Establishment of a new Epstein-Barr virus-immortalized cell line from chronic lymphocytic leukemia with trisomy of chromosome 12 that produces monoclonal IgM against a sheep RBC antigen" @default.
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- W1503816963 doi "https://doi.org/10.1182/blood.v71.1.9.9" @default.
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