Matches in SemOpenAlex for { <https://semopenalex.org/work/W1503830629> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W1503830629 abstract "Only relatively recently have we begun to understand how defibrillation shocks work on the mechanistic level (Cheng et al., 1999; Trayanova & Skouibine, 1998). Virtual electrode polarization has offered a plausible mechanism for explaining far field effects of defibrillation shocks. However, this body of work has not considered the role of the specialized cardiac conduction system, the Purkinje System (PS), in the defibrillation process. Despite its crucial role in activation, relatively little is known about the role of the PS in defibrillation. This is due to several factors which make recording from it challenging: The PS is a fine structure lying on the endocardium which makes it difficult to see and impale with microelectrodes. While Langendorf preparations allow easy access to the epicardium for optical recordings, the PS lies on the endocardium and is, therefore, much harder to access while maintaining the integrity of the ventricles. Depending on species, the PS penetrates various depths into the myocardium, masking midmyocardial activation. Plunge electrodes are one option for recording from the midmyocardium, but amplifier saturation immediately following large shocks would lose important information. Since the PS fibres are fine, the signals produced by them are very small and get easily swamped by signals from the myocardium. This is true for both electrical and optical recordings. Computer modelling, therefore, offers an attractive platform for studying the role of the PS in defibrillation, since the electrical activity everywhere in the system is known and can be visualized." @default.
- W1503830629 created "2016-06-24" @default.
- W1503830629 creator A5065213444 @default.
- W1503830629 creator A5074320734 @default.
- W1503830629 creator A5077129710 @default.
- W1503830629 date "2011-09-26" @default.
- W1503830629 modified "2023-10-03" @default.
- W1503830629 title "The Role of the Purkinje System in Defibrillation" @default.
- W1503830629 cites W150436295 @default.
- W1503830629 cites W1988136878 @default.
- W1503830629 cites W2001897741 @default.
- W1503830629 cites W2012489409 @default.
- W1503830629 cites W2014026887 @default.
- W1503830629 cites W2014514899 @default.
- W1503830629 cites W2015146179 @default.
- W1503830629 cites W2016154727 @default.
- W1503830629 cites W2017556463 @default.
- W1503830629 cites W2027523097 @default.
- W1503830629 cites W2042564404 @default.
- W1503830629 cites W2052375282 @default.
- W1503830629 cites W2055308995 @default.
- W1503830629 cites W2061457365 @default.
- W1503830629 cites W2070024016 @default.
- W1503830629 cites W2071103823 @default.
- W1503830629 cites W2083456832 @default.
- W1503830629 cites W2088342226 @default.
- W1503830629 cites W2097927989 @default.
- W1503830629 cites W2100154504 @default.
- W1503830629 cites W2104701510 @default.
- W1503830629 cites W2108822093 @default.
- W1503830629 cites W2126799459 @default.
- W1503830629 cites W2132062050 @default.
- W1503830629 cites W2140012020 @default.
- W1503830629 cites W2140597992 @default.
- W1503830629 cites W2144877604 @default.
- W1503830629 cites W2157361324 @default.
- W1503830629 cites W2188650473 @default.
- W1503830629 cites W2402802759 @default.
- W1503830629 cites W3151543911 @default.
- W1503830629 cites W380792002 @default.
- W1503830629 doi "https://doi.org/10.5772/25267" @default.
- W1503830629 hasPublicationYear "2011" @default.
- W1503830629 type Work @default.
- W1503830629 sameAs 1503830629 @default.
- W1503830629 citedByCount "0" @default.
- W1503830629 crossrefType "book-chapter" @default.
- W1503830629 hasAuthorship W1503830629A5065213444 @default.
- W1503830629 hasAuthorship W1503830629A5074320734 @default.
- W1503830629 hasAuthorship W1503830629A5077129710 @default.
- W1503830629 hasBestOaLocation W15038306291 @default.
- W1503830629 hasConcept C15744967 @default.
- W1503830629 hasConcept C164705383 @default.
- W1503830629 hasConcept C169760540 @default.
- W1503830629 hasConcept C2777795826 @default.
- W1503830629 hasConcept C71924100 @default.
- W1503830629 hasConceptScore W1503830629C15744967 @default.
- W1503830629 hasConceptScore W1503830629C164705383 @default.
- W1503830629 hasConceptScore W1503830629C169760540 @default.
- W1503830629 hasConceptScore W1503830629C2777795826 @default.
- W1503830629 hasConceptScore W1503830629C71924100 @default.
- W1503830629 hasLocation W15038306291 @default.
- W1503830629 hasLocation W15038306292 @default.
- W1503830629 hasOpenAccess W1503830629 @default.
- W1503830629 hasPrimaryLocation W15038306291 @default.
- W1503830629 hasRelatedWork W126597415 @default.
- W1503830629 hasRelatedWork W1922271755 @default.
- W1503830629 hasRelatedWork W1991669304 @default.
- W1503830629 hasRelatedWork W2025646615 @default.
- W1503830629 hasRelatedWork W2031119379 @default.
- W1503830629 hasRelatedWork W2052464739 @default.
- W1503830629 hasRelatedWork W2066720269 @default.
- W1503830629 hasRelatedWork W2347978082 @default.
- W1503830629 hasRelatedWork W2424823027 @default.
- W1503830629 hasRelatedWork W3140105860 @default.
- W1503830629 isParatext "false" @default.
- W1503830629 isRetracted "false" @default.
- W1503830629 magId "1503830629" @default.
- W1503830629 workType "book-chapter" @default.