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- W1503886996 abstract "To identify prognostic factors prospectively in cirrhosis after the eradication of esophageal varices (EV).There were 52 cirrhosis patients (Child-Pugh A 24, B 28) who showed the eradication of EV after the endoscopic sclerotherapy (median observation period, 25.5 months).Eighteen patients showed a recurrence of EV. The cumulative overall survival rate was 92.2% at 1 year, 70.9% at 3 years, and 47.2% at 5 years. Univariate analysis showed that serum sodium concentration (hazard ratio [HR] 0.724, P = 0.0006), serum aspartate transaminase (HR 1.019, P = 0.0075), serum alanine transaminase (HR 1.025, P = 0.0239), and serum creatinine (HR 11.311, P = 0.044) levels before treatment were significant factors for a poor prognosis. Multivariate analysis revealed that serum sodium concentration (HR 0.711, P = 0.0022) was the only significant factor. The cumulative survival rate was lower in patients with hyponatremia (<135 mEq/l, a best cut-off value; 83.3% at 1 year, and 33.3% at 3 years), than in those without (93.3% at 1 year, 77.3% at 3 years and 47.2% at 5 years).Pre-treatment hyponatremia is a significant prognostic factor in cirrhosis with Child A/B after the eradication of EV by the endoscopic sclerotherapy." @default.
- W1503886996 created "2016-06-24" @default.
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- W1503886996 date "2015-08-28" @default.
- W1503886996 modified "2023-10-16" @default.
- W1503886996 title "Hyponatremia: a significant factor in a poor prognosis for cirrhosis with Child A/B after variceal eradication" @default.
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- W1503886996 doi "https://doi.org/10.1002/jhbp.282" @default.
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