Matches in SemOpenAlex for { <https://semopenalex.org/work/W1504288287> ?p ?o ?g. }
- W1504288287 abstract "1.1 Acute cardiac collapse Patients with cardiogenic shock and cardiac arrest still have a very poor prognosis despite recent improvements in treatment algorithms. Acute coronary ischemia and myocardial infarction (AMI) is the most frequent cause of cardiogenic shock and cardiac arrest. Improved survival has been shown for patients with AMI treated with urgent coronary revascularization. Also, improved pre-hospital logistics and cooling after successful resuscitation has shown possible benefit for cardiac arrest patients. However, a large proportion of patients with AMI and acute cardiac collapse do not survive until hospital discharge. These represent a group where current treatment options are often unsuccessful. This far, advances in pharmacological treatment have produced various substances with theoretical and hemodynamic promise but clinical effects have been scarce. The use of vasopressors and inotropes generally has failed to show effect on mortality in cardiogenic shock and cardiac arrest. Recently a large clinical trial showed no effect of intravenous medication on survival for cardiac arrest victims (Figure 1). Lately, more thought provoking data have emerged indicating a possible negative effect of vasopressor therapy on cardiac and cerebral perfusion during circulatory collapse and resuscitation. Clinical reports have further suggested a possible relationship between the use of adrenaline like drugs and increased mortality in patients with acute myocardial infarction and shock. Mechanical support with intra-aortic balloon pump (IABP) counter pulsation therapy has been routinely used for several years in cardiogenic shock but the clinical usefulness is currently being strongly questioned. In cardiac arrest, optimally performed chest compressions are critical for successful re-establishment of intrinsic pulse giving rhythm (Figure 2). Mechanical compression-decompression devices have also shown impressive hemodynamic effects experimentally but a benefit compared with conventional chest compressions has not been found in clinical trials. Both IABP and the compression-decompression devices have been associated with bleeding complications. The mechanisms behind refractory cardiogenic shock and cardiac arrest may be many and are yet not clearly defined. It seems clear however, that with the pharmacological and" @default.
- W1504288287 created "2016-06-24" @default.
- W1504288287 creator A5067857540 @default.
- W1504288287 creator A5091432568 @default.
- W1504288287 date "2011-04-26" @default.
- W1504288287 modified "2023-10-04" @default.
- W1504288287 title "Future Treatment of Acute Cardiac Collapse - A Role for Percutaneous Circulatory Assist Devices" @default.
- W1504288287 cites W1484497048 @default.
- W1504288287 cites W1592495849 @default.
- W1504288287 cites W1934199184 @default.
- W1504288287 cites W1951517409 @default.
- W1504288287 cites W1963091119 @default.
- W1504288287 cites W1965308117 @default.
- W1504288287 cites W1968871744 @default.
- W1504288287 cites W1968960893 @default.
- W1504288287 cites W1969295152 @default.
- W1504288287 cites W1970855181 @default.
- W1504288287 cites W1973833027 @default.
- W1504288287 cites W1976225175 @default.
- W1504288287 cites W1978655451 @default.
- W1504288287 cites W1979640956 @default.
- W1504288287 cites W1980900994 @default.
- W1504288287 cites W1982173571 @default.
- W1504288287 cites W1982635623 @default.
- W1504288287 cites W1990154321 @default.
- W1504288287 cites W1994993394 @default.
- W1504288287 cites W1995402741 @default.
- W1504288287 cites W1997205359 @default.
- W1504288287 cites W1998252238 @default.
- W1504288287 cites W2000088016 @default.
- W1504288287 cites W2001156487 @default.
- W1504288287 cites W2002829478 @default.
- W1504288287 cites W2004382977 @default.
- W1504288287 cites W2006720976 @default.
- W1504288287 cites W2007735723 @default.
- W1504288287 cites W2008557455 @default.
- W1504288287 cites W2009063341 @default.
- W1504288287 cites W2009086644 @default.
- W1504288287 cites W2010932678 @default.
- W1504288287 cites W2013165626 @default.
- W1504288287 cites W2015285014 @default.
- W1504288287 cites W2016252326 @default.
- W1504288287 cites W2017114258 @default.
- W1504288287 cites W2018772604 @default.
- W1504288287 cites W2018787568 @default.
- W1504288287 cites W2020351146 @default.
- W1504288287 cites W2020765940 @default.
- W1504288287 cites W2026216854 @default.
- W1504288287 cites W2030300897 @default.
- W1504288287 cites W2030770340 @default.
- W1504288287 cites W2031033928 @default.
- W1504288287 cites W2040442722 @default.
- W1504288287 cites W2041246806 @default.
- W1504288287 cites W2041306249 @default.
- W1504288287 cites W2043429881 @default.
- W1504288287 cites W2047311925 @default.
- W1504288287 cites W2049564255 @default.
- W1504288287 cites W2050338922 @default.
- W1504288287 cites W2050521356 @default.
- W1504288287 cites W2051110774 @default.
- W1504288287 cites W2052693000 @default.
- W1504288287 cites W2053081693 @default.
- W1504288287 cites W2054153573 @default.
- W1504288287 cites W2054553973 @default.
- W1504288287 cites W2057633381 @default.
- W1504288287 cites W2059482126 @default.
- W1504288287 cites W2062642814 @default.
- W1504288287 cites W2062739893 @default.
- W1504288287 cites W2067908653 @default.
- W1504288287 cites W2069948001 @default.
- W1504288287 cites W2070616514 @default.
- W1504288287 cites W2074644050 @default.
- W1504288287 cites W2075881701 @default.
- W1504288287 cites W2078331807 @default.
- W1504288287 cites W2080326395 @default.
- W1504288287 cites W2082404562 @default.
- W1504288287 cites W2083893789 @default.
- W1504288287 cites W2085702855 @default.
- W1504288287 cites W2086310062 @default.
- W1504288287 cites W2086551905 @default.
- W1504288287 cites W2087461041 @default.
- W1504288287 cites W2087651862 @default.
- W1504288287 cites W2092103008 @default.
- W1504288287 cites W2098404000 @default.
- W1504288287 cites W2110901792 @default.
- W1504288287 cites W2111942450 @default.
- W1504288287 cites W2117730908 @default.
- W1504288287 cites W2120013505 @default.
- W1504288287 cites W2120090810 @default.
- W1504288287 cites W2120916423 @default.
- W1504288287 cites W2125797678 @default.
- W1504288287 cites W2128323523 @default.
- W1504288287 cites W2131264636 @default.
- W1504288287 cites W2141167900 @default.
- W1504288287 cites W2143695906 @default.
- W1504288287 cites W2148810509 @default.
- W1504288287 cites W2150947866 @default.
- W1504288287 cites W2153019706 @default.
- W1504288287 cites W2155220576 @default.
- W1504288287 cites W2159572870 @default.