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• W1504328175 abstract "Three patients with chronic mucocutaneous candidiasis were found to have an immune defect consisting of inability to manifest delayed hypersensitivity to skin tests or to active sensitisation with 2,4-dinitrofluorobenzene. Two of these patients demonstrated a selective defect in parotid-fluid IgA antibody directed against Candida albicans. The quantity and distribution of salivary immunoglobulins were normal. In-vitro response of the patient's lymphocytes to both specific (C. albicans) and non-specific (phytohæmagglutinin) mitogenic stimulation was normal. In contrast, other patients with chronic mucocutaneous candidiasis manifested delayed hypersensitivity and demonstrated high levels of C. albicans specific IgA antibody in parotid fluid. This suggests that an immunological deficiency may account for some forms of chronic mucocutaneous candidiasis." @default.
• W1504328175 created "2016-06-24" @default.
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• W1504328175 date "1967-09-01" @default.
• W1504328175 modified "2023-10-06" @default.
• W1504328175 title "CHRONIC MUCOCUTANEOUS CANDIDIASIS, DEFICIENCY OF DELAYED" @default.
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• W1504328175 doi "https://doi.org/10.1016/s0140-6736(67)90974-9" @default.
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