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W1504491036 abstract "Limited epidemiological evidence suggests a protective role for plant foods rich in flavonoids and antioxidants in hepatocellular cancer (HCC) etiology. Our aim was to prospectively investigate the association between dietary intake of flavonoids, lignans and nonenzymatic antioxidant capacity (NEAC) and HCC risk. Data from the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort including 477,206 subjects (29.8% male) recruited from ten Western European countries, was analyzed. Flavonoid, lignan and NEAC intakes were calculated using a compilation of existing food composition databases linked to dietary information from validated dietary questionnaires. Dietary NEAC was based on ferric reducing antioxidant capacity (FRAP) and total radical‐trapping antioxidant parameter (TRAP). Hepatitis B/C status was measured in a nested case–control subset. During a mean follow‐up of 11‐years, 191 incident HCC cases (66.5% men) were identified. Using Cox regression, multivariable adjusted models showed a borderline nonsignificant association of HCC with total flavonoid intake (highest versus lowest tertile, HR = 0.65, 95% CI: 0.40–1.04; p trend = 0.065), but not with lignans. Among flavonoid subclasses, flavanols were inversely associated with HCC risk (HR = 0.62, 95% CI: 0.39–0.99; p trend = 0.06). Dietary NEAC was inversely associated with HCC (FRAP: HR 0.50, 95% CI: 0.31–0.81; p trend = 0.001; TRAP: HR 0.49, 95% CI: 0.31–0.79; p trend = 0.002), but statistical significance was lost after exclusion of the first 2 years of follow‐up. This study suggests that higher intake of dietary flavanols and antioxidants may be associated with a reduced HCC risk." @default.
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W1504491036 date "2013-06-04" @default.
W1504491036 modified "2023-10-18" @default.
W1504491036 title "Dietary flavonoid, lignan and antioxidant capacity and risk of hepatocellular carcinoma in the European prospective investigation into cancer and nutrition study" @default.
W1504491036 cites W1895964898 @default.
W1504491036 cites W1908802886 @default.
W1504491036 cites W1914843938 @default.
W1504491036 cites W1950940723 @default.
W1504491036 cites W1964078834 @default.
W1504491036 cites W1965234101 @default.
W1504491036 cites W1965921863 @default.
W1504491036 cites W1969787232 @default.
W1504491036 cites W1979835159 @default.
W1504491036 cites W1981989535 @default.
W1504491036 cites W1984048346 @default.
W1504491036 cites W1998053609 @default.
W1504491036 cites W2028210004 @default.
W1504491036 cites W2036860790 @default.
W1504491036 cites W2039368155 @default.
W1504491036 cites W2039691683 @default.
W1504491036 cites W2040740169 @default.
W1504491036 cites W2046808936 @default.
W1504491036 cites W2074972394 @default.
W1504491036 cites W2082880246 @default.
W1504491036 cites W2089482945 @default.
W1504491036 cites W2090374493 @default.
W1504491036 cites W2091047906 @default.
W1504491036 cites W2094754482 @default.
W1504491036 cites W2099581302 @default.
W1504491036 cites W2102321716 @default.
W1504491036 cites W2103823644 @default.
W1504491036 cites W2104064239 @default.
W1504491036 cites W2109219853 @default.
W1504491036 cites W2119331100 @default.
W1504491036 cites W2124098523 @default.
W1504491036 cites W2130479712 @default.
W1504491036 cites W2130539506 @default.
W1504491036 cites W2135657957 @default.
W1504491036 cites W2137417655 @default.
W1504491036 cites W2144219918 @default.
W1504491036 cites W2144862608 @default.
W1504491036 cites W2148841223 @default.
W1504491036 cites W2155098460 @default.
W1504491036 cites W2155530251 @default.
W1504491036 cites W2157043395 @default.
W1504491036 cites W2158701669 @default.
W1504491036 cites W2161364465 @default.
W1504491036 doi "https://doi.org/10.1002/ijc.28257" @default.
W1504491036 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23649669" @default.
W1504491036 hasPublicationYear "2013" @default.
W1504491036 type Work @default.