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- W1504890693 abstract "In the present study a gene encoding PPE protein of M.a.paratuberculosis (FJ032182) was cloned with murine IFN-³ in a mammalian bicistronic vector pIRES 6.1 to elucidate the role of gamma interferon on the PPE gene for determination of CD4/CD8 ratio in post immunized mice. Flow cytometric analysis with mononuclear mice splenocytes on 42nd day post immunization revealed significant reduction of the CD4/CD8 ratio in the mice group immunized with pIR PPE/IFN (1.65±0.0001) compared to the pIR PPE group (2.92±0.0003). These result suggested that co-expression of murine IFNg in conjunction with PPE protein significantly enhanced the CMI response." @default.
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- W1504890693 date "2013-01-01" @default.
- W1504890693 modified "2023-09-23" @default.
- W1504890693 title "Detection of CD4/CD8 ratio in mice immunized with a bicistronic plasmid construct encoding a ppe gene of Mycobacterium avium paratuberculosis and a cytokine gene of murine gamma interferon*" @default.
- W1504890693 hasPublicationYear "2013" @default.
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