Matches in SemOpenAlex for { <https://semopenalex.org/work/W1505008093> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W1505008093 endingPage "1339" @default.
- W1505008093 startingPage "1333" @default.
- W1505008093 abstract "Current concepts of protein turnover, synthesis, and breakdown in man are reviewed. Emphasis is placed on the distinction between protein breakdown, by which constituent amino acids are released, and amino acid catabolism, which leads to the formation of excretory products, mainly urea and carbon dioxide. Methods of measuring overall rates of turnover, synthesis, and breakdown of body protein in man by the continuous or intermittent administration of radioactive or stable isotopes of amino acids are reviewed. Data from the published literature and from ongoing studies reveal that the overall rate of protein synthesis declines with age. There is close agreement between results obtained with different isotopes in normal adults. Malnourished infants have significantly lower rates of protein turnover, synthesis, and breakdown before than after recovery. These findings may represent another example of metabolic adaptation in the malnourished child. After surgical trauma in adults, the rate of protein synthesis is significantly reduced and neither protein turnover nor breakdown shows a significant change from preoperative values. It is conciuded from these studies that the negative nitrogen balance found after injury is accounted for by a reduction in protein synthesis and that protein breakdown remains unchanged after orthopedic operations. The relevance of these findings to the changes in nitrogen metabolism seen in infection is discussed." @default.
- W1505008093 created "2016-06-24" @default.
- W1505008093 creator A5052673891 @default.
- W1505008093 creator A5061578429 @default.
- W1505008093 creator A5084433250 @default.
- W1505008093 date "1977-08-01" @default.
- W1505008093 modified "2023-09-27" @default.
- W1505008093 title "The measurement of rates of protein turnover, synthesis, and breakdown in man and the effects of nutritional status and surgical injury" @default.
- W1505008093 cites W104378601 @default.
- W1505008093 cites W2051292368 @default.
- W1505008093 cites W2057365575 @default.
- W1505008093 cites W2064920452 @default.
- W1505008093 cites W2102557633 @default.
- W1505008093 cites W2119077294 @default.
- W1505008093 doi "https://doi.org/10.1093/ajcn/30.8.1333" @default.
- W1505008093 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/407787" @default.
- W1505008093 hasPublicationYear "1977" @default.
- W1505008093 type Work @default.
- W1505008093 sameAs 1505008093 @default.
- W1505008093 citedByCount "56" @default.
- W1505008093 countsByYear W15050080932017 @default.
- W1505008093 countsByYear W15050080932019 @default.
- W1505008093 countsByYear W15050080932020 @default.
- W1505008093 countsByYear W15050080932021 @default.
- W1505008093 crossrefType "journal-article" @default.
- W1505008093 hasAuthorship W1505008093A5052673891 @default.
- W1505008093 hasAuthorship W1505008093A5061578429 @default.
- W1505008093 hasAuthorship W1505008093A5084433250 @default.
- W1505008093 hasBestOaLocation W15050080931 @default.
- W1505008093 hasConcept C126322002 @default.
- W1505008093 hasConcept C178790620 @default.
- W1505008093 hasConcept C185592680 @default.
- W1505008093 hasConcept C195580219 @default.
- W1505008093 hasConcept C197683979 @default.
- W1505008093 hasConcept C2779572773 @default.
- W1505008093 hasConcept C2992195973 @default.
- W1505008093 hasConcept C3675279 @default.
- W1505008093 hasConcept C515207424 @default.
- W1505008093 hasConcept C537208039 @default.
- W1505008093 hasConcept C55493867 @default.
- W1505008093 hasConcept C62231903 @default.
- W1505008093 hasConcept C71924100 @default.
- W1505008093 hasConcept C8101879 @default.
- W1505008093 hasConcept C96942376 @default.
- W1505008093 hasConceptScore W1505008093C126322002 @default.
- W1505008093 hasConceptScore W1505008093C178790620 @default.
- W1505008093 hasConceptScore W1505008093C185592680 @default.
- W1505008093 hasConceptScore W1505008093C195580219 @default.
- W1505008093 hasConceptScore W1505008093C197683979 @default.
- W1505008093 hasConceptScore W1505008093C2779572773 @default.
- W1505008093 hasConceptScore W1505008093C2992195973 @default.
- W1505008093 hasConceptScore W1505008093C3675279 @default.
- W1505008093 hasConceptScore W1505008093C515207424 @default.
- W1505008093 hasConceptScore W1505008093C537208039 @default.
- W1505008093 hasConceptScore W1505008093C55493867 @default.
- W1505008093 hasConceptScore W1505008093C62231903 @default.
- W1505008093 hasConceptScore W1505008093C71924100 @default.
- W1505008093 hasConceptScore W1505008093C8101879 @default.
- W1505008093 hasConceptScore W1505008093C96942376 @default.
- W1505008093 hasIssue "8" @default.
- W1505008093 hasLocation W15050080931 @default.
- W1505008093 hasLocation W15050080932 @default.
- W1505008093 hasOpenAccess W1505008093 @default.
- W1505008093 hasPrimaryLocation W15050080931 @default.
- W1505008093 hasRelatedWork W1505008093 @default.
- W1505008093 hasRelatedWork W1578211856 @default.
- W1505008093 hasRelatedWork W1642498015 @default.
- W1505008093 hasRelatedWork W1887188565 @default.
- W1505008093 hasRelatedWork W1972297093 @default.
- W1505008093 hasRelatedWork W201560875 @default.
- W1505008093 hasRelatedWork W2104078959 @default.
- W1505008093 hasRelatedWork W2130053863 @default.
- W1505008093 hasRelatedWork W2136519953 @default.
- W1505008093 hasRelatedWork W2141461788 @default.
- W1505008093 hasVolume "30" @default.
- W1505008093 isParatext "false" @default.
- W1505008093 isRetracted "false" @default.
- W1505008093 magId "1505008093" @default.
- W1505008093 workType "article" @default.