FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1505211334> ?p ?o ?g. }

• W1505211334 endingPage "6" @default.
• W1505211334 startingPage "4113" @default.
• W1505211334 abstract "To investigate whether interleukin 6 (IL-6) might be a potential mediator of the depleted fat reserves observed in malignancy-associated cachexia, we measured lipoprotein lipase (LPL) activity in adipose tissue of mice after administration of IL-6 or tumor necrosis factor and in cultured adipocytes after addition of these cytokines. Injection of IL-6 i.p. reduced adipose tissue LPL activity by 53% within 4.5 to 5.5 h. Injection of tumor necrosis factor elevated serum IL-6 levels and reduced adipose tissue LPL activity by 70%. Both human and murine IL-6 reduced heparin-releasable LPL activity in 3T3-L1 adipocytes in a dose-dependent manner; half-maximal inhibition of LPL activity was achieved with 5000 hybridoma growth factor units/ml. Thus, IL-6 reduces adipose LPL activity and may contribute to the loss of body fat stores associated with some cases of cancer cachexia. Since tumor necrosis factor increases circulating IL-6, some of its effects may be mediated or potentiated by IL-6." @default.
• W1505211334 created "2016-06-24" @default.
• W1505211334 creator A5014977535 @default.
• W1505211334 creator A5023877788 @default.
• W1505211334 creator A5031906759 @default.
• W1505211334 creator A5083132381 @default.
• W1505211334 creator A5083976565 @default.
• W1505211334 creator A5084397317 @default.
• W1505211334 date "1992-08-01" @default.
• W1505211334 modified "2023-09-23" @default.
• W1505211334 title "Interleukin 6 reduces lipoprotein lipase activity in adipose tissue of mice in vivo and in 3T3-L1 adipocytes: a possible role for interleukin 6 in cancer cachexia." @default.
• W1505211334 cites W1516684647 @default.
• W1505211334 cites W1523366628 @default.
• W1505211334 cites W1546868324 @default.
• W1505211334 cites W1555931521 @default.
• W1505211334 cites W1575331985 @default.
• W1505211334 cites W157721590 @default.
• W1505211334 cites W1657108383 @default.
• W1505211334 cites W1908254726 @default.
• W1505211334 cites W1956105050 @default.
• W1505211334 cites W1973965625 @default.
• W1505211334 cites W1992071813 @default.
• W1505211334 cites W1996755666 @default.
• W1505211334 cites W2004556731 @default.
• W1505211334 cites W2006102382 @default.
• W1505211334 cites W2006704738 @default.
• W1505211334 cites W2008251212 @default.
• W1505211334 cites W2023972192 @default.
• W1505211334 cites W2026838950 @default.
• W1505211334 cites W2037423583 @default.
• W1505211334 cites W2060302354 @default.
• W1505211334 cites W2092042022 @default.
• W1505211334 cites W2094115400 @default.
• W1505211334 cites W2101836190 @default.
• W1505211334 cites W2103933115 @default.
• W1505211334 cites W2135392289 @default.
• W1505211334 cites W2139731919 @default.
• W1505211334 cites W2142585662 @default.
• W1505211334 cites W2159297751 @default.
• W1505211334 cites W2165314511 @default.
• W1505211334 cites W2219187893 @default.
• W1505211334 cites W2220000844 @default.
• W1505211334 cites W2236782747 @default.
• W1505211334 cites W2343078807 @default.
• W1505211334 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1638523" @default.
• W1505211334 hasPublicationYear "1992" @default.
• W1505211334 type Work @default.
• W1505211334 sameAs 1505211334 @default.
• W1505211334 citedByCount "95" @default.
• W1505211334 countsByYear W15052113342012 @default.
• W1505211334 countsByYear W15052113342014 @default.
• W1505211334 countsByYear W15052113342015 @default.
• W1505211334 countsByYear W15052113342016 @default.
• W1505211334 countsByYear W15052113342017 @default.
• W1505211334 countsByYear W15052113342018 @default.
• W1505211334 countsByYear W15052113342019 @default.
• W1505211334 countsByYear W15052113342020 @default.
• W1505211334 countsByYear W15052113342022 @default.
• W1505211334 countsByYear W15052113342023 @default.
• W1505211334 crossrefType "journal-article" @default.
• W1505211334 hasAuthorship W1505211334A5014977535 @default.
• W1505211334 hasAuthorship W1505211334A5023877788 @default.
• W1505211334 hasAuthorship W1505211334A5031906759 @default.
• W1505211334 hasAuthorship W1505211334A5083132381 @default.
• W1505211334 hasAuthorship W1505211334A5083976565 @default.
• W1505211334 hasAuthorship W1505211334A5084397317 @default.
• W1505211334 hasConcept C11988809 @default.
• W1505211334 hasConcept C121608353 @default.
• W1505211334 hasConcept C126322002 @default.
• W1505211334 hasConcept C134018914 @default.
• W1505211334 hasConcept C171089720 @default.
• W1505211334 hasConcept C17991360 @default.
• W1505211334 hasConcept C185592680 @default.
• W1505211334 hasConcept C2776175234 @default.
• W1505211334 hasConcept C2777704314 @default.
• W1505211334 hasConcept C2778690821 @default.
• W1505211334 hasConcept C71924100 @default.
• W1505211334 hasConcept C74172505 @default.
• W1505211334 hasConcept C86803240 @default.
• W1505211334 hasConcept C94879076 @default.
• W1505211334 hasConceptScore W1505211334C11988809 @default.
• W1505211334 hasConceptScore W1505211334C121608353 @default.
• W1505211334 hasConceptScore W1505211334C126322002 @default.
• W1505211334 hasConceptScore W1505211334C134018914 @default.
• W1505211334 hasConceptScore W1505211334C171089720 @default.
• W1505211334 hasConceptScore W1505211334C17991360 @default.
• W1505211334 hasConceptScore W1505211334C185592680 @default.
• W1505211334 hasConceptScore W1505211334C2776175234 @default.
• W1505211334 hasConceptScore W1505211334C2777704314 @default.
• W1505211334 hasConceptScore W1505211334C2778690821 @default.
• W1505211334 hasConceptScore W1505211334C71924100 @default.
• W1505211334 hasConceptScore W1505211334C74172505 @default.
• W1505211334 hasConceptScore W1505211334C86803240 @default.
• W1505211334 hasConceptScore W1505211334C94879076 @default.
• W1505211334 hasIssue "15" @default.
• W1505211334 hasLocation W15052113341 @default.
• W1505211334 hasOpenAccess W1505211334 @default.
• W1505211334 hasPrimaryLocation W15052113341 @default.

• next