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- W1505254265 abstract "Summary For treatment of several malignancies, transplantation of allogeneic haematopoietic stem cells (HSCT) derived from bone marrow or peripheral blood has been used as a therapeutic procedure for decades. In the past, HSCT has been suggested as a treatment option for infection with the human immunodeficiency virus type 1 (HIV-1), but these attempts were mostly unsuccessful. Today, after the introduction of an active anti-retroviral therapy, the lifetime expectancy of HIV-infected patients has improved substantially, but nevertheless the incidence rate of malignancies in these patients has increased considerably. Therefore, it can be assumed that there will be a rising necessity for HIV-1-infected patients with malignancies for allogeneic HSCT. At the same time, there is increasing interest in treatment methods which might target the HIV-1 reservoir more effectively, and the question has been raised as to whether allogeneic HSCT could be linked to such strategies. In this paper the data of more than 25 years experience with allogeneic HSCT in patients with HIV-1 are reviewed and analysed." @default.
- W1505254265 created "2016-06-24" @default.
- W1505254265 creator A5061721634 @default.
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- W1505254265 date "2011-02-08" @default.
- W1505254265 modified "2023-10-02" @default.
- W1505254265 title "Allogeneic haematopoietic stem cell transplantation in patients with human immunodeficiency virus: the experiences of more than 25 years" @default.
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- W1505254265 doi "https://doi.org/10.1111/j.1365-2249.2010.04312.x" @default.
- W1505254265 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3048611" @default.
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