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- W1505284252 abstract "Bronchopulmonary dysplasia (BPD) is the most common adverse outcome in extreme preterm neonates (born before 28 weeks gestation). BPD is characterized by interrupted lung growth and may predispose to early-onset emphysema and poor lung function in later life. At present, there is no treatment for BPD. Recent advances in stem/progenitor cell biology have enabled the exploration of endogenous lung progenitor populations in health and disease. In parallel, exogenous stem/progenitor cell administration has shown promise in protecting the lung from injury in the experimental setting. This review will provide an outline of the progenitor populations that have currently been identified in all tissue compartments of the distal lung and how they may be affected in BPD. A thorough understanding of the lung's endogenous progenitor populations during normal development, injury and repair may one day allow us to harness their regenerative capacity." @default.
- W1505284252 created "2016-06-24" @default.
- W1505284252 creator A5051658775 @default.
- W1505284252 creator A5073013772 @default.
- W1505284252 date "2014-03-01" @default.
- W1505284252 modified "2023-10-16" @default.
- W1505284252 title "Progenitor cells of the distal lung and their potential role in neonatal lung disease" @default.
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- W1505284252 doi "https://doi.org/10.1002/bdra.23227" @default.
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