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• W1505531553 abstract "Acute mountain sickness (AMS) is a common problem while ascending at high altitude. AMS may progress rapidly with fatal results if the acclimatization process fails or symptoms are neglected and the ascent continues. It affects 25% of those ascending to altitudes of 1850 to 2750 m, 42% at altitudes of 3000 m, and even 84% of those attempting a tourist flight to Lhasa, Tibet (3860 m). The most common reason for altitude illness is a too rapid ascent. There is a need for a non-invasive, specific, and convenient field method for the detection of inadequate acclimatization and impending AMS. Arterial oxygen saturation (SpO 2 ) measurement is useful in anticipating AMS, but it is susceptible to many disruptive factors in the field (for example temperature). Autonomic cardiac response to increasing altitude could be a low-cost non-invasive test to predict impending AMS, in addition to helping distinguish those who are at risk for AMS and those who are acclimatizing well. The purpose of the present study was to: 1. assess the prevalence of the symptoms and signs of acute mountain sickness among Finnish travelers climbing Mount Kilimanjaro, Tanzania; 2. investigate if post-exercise oxygen saturation (Ex-SpO2) at high altitudes predicts AMS better than arterial O 2 saturation at rest (R-SpO 2 ) or resting heart rate (HR) alone; 3. evaluate if heart rate variation (HRV) level or HRV changes have a relationship to AMS during ascent and provide new information on the deterioration of cardiac autonomic function as measured by HRV, not only at altitudes between 2400 and 5000 m, which are most frequent among climbers, but also at extreme altitudes above 5000 m in field conditions; 4. generate tools for AMS for non-medical persons to estimate the risk in field conditions; and 5. describe a typical AMS case and the difficulties to treat AMS at field conditions. The data was collected during several treks to Kilimanjaro and climbing expeditions to Denali, Shisha Pangma, Ulugh Muztagh, Island Peak, and Mount Everest 2001-2009. The incidence of AMS was very high (75%) for the trekkers at Mt Kilimanjaro. In climbing expeditions, subjects susceptible to AMS had lower SpO 2 at rest and especially during exercise before the clinical manifestations of AMS so daily measurements of SpO 2 were taken at these times to best predict the subsequent AMS at higher altitude if ascending continued. Subjects susceptible to AMS had lower root mean square successive differences and high-frequency power of HRV before the clinical manifestations of AMS than those who acclimatized well and did not get AMS 2-5 days later if ascending continued. The treatment of AMS in the field is difficult and time consuming, where possibilities for medical treatment and oxygen substitution might be limited. Prevention is the safest and the most efficient method of care. Realising the risk of mountain sickness, active inquiry about symptoms and correctly timed reaction to them, in other words interrupting the ascent or descending, helps to reduce, and even to prevent, the development of serious problems." @default.
• W1505531553 created "2016-06-24" @default.
• W1505531553 creator A5006983264 @default.
• W1505531553 date "2013-09-27" @default.
• W1505531553 modified "2023-09-25" @default.
• W1505531553 title "Acute mountain sickness : prediction and treatment during climbing expeditions" @default.
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