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• W1506578365 abstract "Abstract There is growing evidence that genomic instability is both an epiphenomenon and a leading cause of cancer. Chromosomal instability in neoplasia (CIN) is the most frequent type of genomic instability in solid tumours. For more than a century, chromosomal rearrangements and aneuploidy in neoplasia have been extensively studied and a vast number of genes and pathways, directly or indirectly implicated in CIN, have been described. Chromosomal abnormalities in cancer generate huge genomic imbalances and tumour heterogeneity. This chapter addresses the role of genes, chromosome structure, and telomere dysfunction in the initiation and perpetuation of CIN. The biological consequences of large chromosomal imbalances are discussed and the long‐standing hypotheses for the generation of chromosomal anomalies in neoplasia are re‐examined under the context of telomere dysfunction and restoration." @default.
• W1506578365 created "2016-06-24" @default.
• W1506578365 creator A5083675818 @default.
• W1506578365 date "2007-10-15" @default.
• W1506578365 modified "2023-10-10" @default.
• W1506578365 title "Genomic Instability and <scp>DNA</scp> Repair" @default.
• W1506578365 cites W1484187172 @default.
• W1506578365 cites W1488719611 @default.
• W1506578365 cites W1496772673 @default.
• W1506578365 cites W1504303645 @default.
• W1506578365 cites W1541877559 @default.
• W1506578365 cites W1544851750 @default.
• W1506578365 cites W1589758056 @default.
• W1506578365 cites W1593569677 @default.
• W1506578365 cites W1600373583 @default.
• W1506578365 cites W1612755896 @default.
• W1506578365 cites W1644986253 @default.
• W1506578365 cites W1676646253 @default.
• W1506578365 cites W1821654469 @default.
• W1506578365 cites W1829553711 @default.
• W1506578365 cites W1964050666 @default.
• W1506578365 cites W1964543951 @default.
• W1506578365 cites W1965336663 @default.
• W1506578365 cites W1965505970 @default.
• W1506578365 cites W1967304777 @default.
• W1506578365 cites W1967587710 @default.
• W1506578365 cites W1970378023 @default.
• W1506578365 cites W1971503458 @default.
• W1506578365 cites W1974058909 @default.
• W1506578365 cites W1974115274 @default.
• W1506578365 cites W1975772358 @default.
• W1506578365 cites W1976273464 @default.
• W1506578365 cites W1977279007 @default.
• W1506578365 cites W1977488724 @default.
• W1506578365 cites W1979141644 @default.
• W1506578365 cites W1980725176 @default.
• W1506578365 cites W1980744528 @default.
• W1506578365 cites W1983385891 @default.
• W1506578365 cites W1983673827 @default.
• W1506578365 cites W1985910710 @default.
• W1506578365 cites W1990085600 @default.
• W1506578365 cites W1990317973 @default.
• W1506578365 cites W1991658194 @default.
• W1506578365 cites W1994419156 @default.
• W1506578365 cites W1995819860 @default.
• W1506578365 cites W1999403469 @default.
• W1506578365 cites W2000971601 @default.
• W1506578365 cites W2001063090 @default.
• W1506578365 cites W2003890314 @default.
• W1506578365 cites W2008720155 @default.
• W1506578365 cites W2008799566 @default.
• W1506578365 cites W2011112706 @default.
• W1506578365 cites W2011281622 @default.
• W1506578365 cites W2011912935 @default.
• W1506578365 cites W2012955490 @default.
• W1506578365 cites W2013073993 @default.
• W1506578365 cites W2013964363 @default.
• W1506578365 cites W2014013625 @default.
• W1506578365 cites W2016656445 @default.
• W1506578365 cites W2017158973 @default.
• W1506578365 cites W2018369441 @default.
• W1506578365 cites W2019163081 @default.
• W1506578365 cites W2020329784 @default.
• W1506578365 cites W2022013301 @default.
• W1506578365 cites W2024619097 @default.
• W1506578365 cites W2025791374 @default.
• W1506578365 cites W2026315272 @default.
• W1506578365 cites W2029531565 @default.
• W1506578365 cites W2030086669 @default.
• W1506578365 cites W2031059869 @default.
• W1506578365 cites W2032267444 @default.
• W1506578365 cites W2034269086 @default.
• W1506578365 cites W2034329129 @default.
• W1506578365 cites W2035389897 @default.
• W1506578365 cites W2035939797 @default.
• W1506578365 cites W2037139254 @default.
• W1506578365 cites W2039517468 @default.
• W1506578365 cites W2040753532 @default.
• W1506578365 cites W2041417130 @default.
• W1506578365 cites W2042889829 @default.
• W1506578365 cites W2043204829 @default.
• W1506578365 cites W2044758458 @default.
• W1506578365 cites W2045448955 @default.
• W1506578365 cites W2046928699 @default.
• W1506578365 cites W2050441340 @default.
• W1506578365 cites W2051337104 @default.
• W1506578365 cites W2051502996 @default.
• W1506578365 cites W2051827116 @default.
• W1506578365 cites W2053620236 @default.
• W1506578365 cites W2058948808 @default.
• W1506578365 cites W2059190311 @default.
• W1506578365 cites W2059492365 @default.
• W1506578365 cites W2060055311 @default.
• W1506578365 cites W2060172889 @default.
• W1506578365 cites W2061805545 @default.
• W1506578365 cites W2062093164 @default.
• W1506578365 cites W2063450668 @default.
• W1506578365 cites W2063914679 @default.
• W1506578365 cites W2064358122 @default.
• W1506578365 cites W2064727462 @default.

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