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• W1506588908 abstract "Sunlight exposure and aging are two major factors in the deterioration of skin function. In the present study, we used eighty formalin-fixed human skin samples from sun-exposed and unexposed areas from old and young individuals to evaluate the presence of miR-125b-positive epidermal stem cells (ESCs) by in situ hybridization. miR-125b-positive ESCs were detected in the basal layer of the epidermis. The density of miR-125b-positive ESCs was significantly associated with age rather than sun exposure, whereas the density of miR-125b-positive ESCs tended to decrease in the sun-exposed area. These data suggest the potential use of miR-125b as a surrogate marker for the quality of epidermal cells." @default.
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• W1506588908 date "2015-06-17" @default.
• W1506588908 modified "2023-10-17" @default.
• W1506588908 title "Aging rather than sun exposure is a major determining factor for the density ofmiR-125b-positive epidermal stem cells in human skin" @default.
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• W1506588908 doi "https://doi.org/10.1111/pin.12320" @default.
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