FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1506724815> ?p ?o ?g. }

• W1506724815 endingPage "540" @default.
• W1506724815 startingPage "533" @default.
• W1506724815 abstract "J Oral Pathol Med (2011) 40: 533–540 Background: Assessing epithelial dysplasia to predict malignant transformation remains problematic in many tissues because grading systems are poorly structured and individual features poorly defined. Dysplasia grading is criticised for lack of reproducibility and poor predictive value. Grading systems for upper aerodigestive tract dysplasia have evolved over several decades and are not supported by good outcome experimental data. Methods: This study analysed the individual features of dysplasia in 86 oral dysplastic lesions and determined the reproducibility of scoring for each, and correlated them with other features and clinical factors using complex clustering analyses. Results: A uniform pattern of dysplasia was found in 37 lesions, focal dysplasia in 36 and in 13 lesions dysplasia formed complex discontinuous patterns. There was wide variation in reproducibility of scoring of individual features and many, including thickness, some types of rete morphology, basaloid cell anisonucleosis, basal dyscohesion, and dyskeratosis as deep single cells correlated with sub-sites. Rete morphology, type of keratinisation, hyperchromatism of the basaloid compartment, prickle cell anisonucleosis and extension down salivary ducts correlated with smoking. Conventional grading and oral intraepithelial neoplasia (OIN) grading by ‘thirds affected’ showed strong correlation overall but scores obtained with the OIN system tended to a higher grade at all sites except soft palate/fauces. There was poor correlation between the systems for moderate dysplasia and also severe dysplasia at some sites. Individual features could not be shown to cluster to form distinct patterns of dysplasia. Conclusions: These variations may account in part for the lack of reproducibility and poor predictive value of the grading systems in current use and could inform the design of future grading systems." @default.
• W1506724815 created "2016-06-24" @default.
• W1506724815 creator A5013013702 @default.
• W1506724815 creator A5022033666 @default.
• W1506724815 creator A5023965559 @default.
• W1506724815 creator A5052149468 @default.
• W1506724815 date "2011-04-18" @default.
• W1506724815 modified "2023-09-27" @default.
• W1506724815 title "Grading oral epithelial dysplasia: analysis of individual features" @default.
• W1506724815 cites W1544146655 @default.
• W1506724815 cites W1972958410 @default.
• W1506724815 cites W1974620690 @default.
• W1506724815 cites W1977114408 @default.
• W1506724815 cites W1984112421 @default.
• W1506724815 cites W1991705545 @default.
• W1506724815 cites W1994005651 @default.
• W1506724815 cites W2009843973 @default.
• W1506724815 cites W2024970640 @default.
• W1506724815 cites W2029762417 @default.
• W1506724815 cites W2036891254 @default.
• W1506724815 cites W2051239172 @default.
• W1506724815 cites W2053416121 @default.
• W1506724815 cites W2062445844 @default.
• W1506724815 cites W2067927788 @default.
• W1506724815 cites W2071813608 @default.
• W1506724815 cites W2075550848 @default.
• W1506724815 cites W2089059310 @default.
• W1506724815 cites W2092127553 @default.
• W1506724815 cites W2102506932 @default.
• W1506724815 cites W2112690682 @default.
• W1506724815 cites W2114492159 @default.
• W1506724815 cites W2159517747 @default.
• W1506724815 cites W4238350906 @default.
• W1506724815 cites W4251737152 @default.
• W1506724815 doi "https://doi.org/10.1111/j.1600-0714.2011.01033.x" @default.
• W1506724815 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21501232" @default.
• W1506724815 hasPublicationYear "2011" @default.
• W1506724815 type Work @default.
• W1506724815 sameAs 1506724815 @default.
• W1506724815 citedByCount "59" @default.
• W1506724815 countsByYear W15067248152012 @default.
• W1506724815 countsByYear W15067248152013 @default.
• W1506724815 countsByYear W15067248152014 @default.
• W1506724815 countsByYear W15067248152015 @default.
• W1506724815 countsByYear W15067248152016 @default.
• W1506724815 countsByYear W15067248152017 @default.
• W1506724815 countsByYear W15067248152018 @default.
• W1506724815 countsByYear W15067248152019 @default.
• W1506724815 countsByYear W15067248152020 @default.
• W1506724815 countsByYear W15067248152021 @default.
• W1506724815 countsByYear W15067248152022 @default.
• W1506724815 countsByYear W15067248152023 @default.
• W1506724815 crossrefType "journal-article" @default.
• W1506724815 hasAuthorship W1506724815A5013013702 @default.
• W1506724815 hasAuthorship W1506724815A5022033666 @default.
• W1506724815 hasAuthorship W1506724815A5023965559 @default.
• W1506724815 hasAuthorship W1506724815A5052149468 @default.
• W1506724815 hasConcept C121608353 @default.
• W1506724815 hasConcept C126322002 @default.
• W1506724815 hasConcept C142724271 @default.
• W1506724815 hasConcept C18903297 @default.
• W1506724815 hasConcept C2775894508 @default.
• W1506724815 hasConcept C2776235491 @default.
• W1506724815 hasConcept C2777286243 @default.
• W1506724815 hasConcept C2777550702 @default.
• W1506724815 hasConcept C2779534503 @default.
• W1506724815 hasConcept C2781340805 @default.
• W1506724815 hasConcept C71924100 @default.
• W1506724815 hasConcept C86803240 @default.
• W1506724815 hasConceptScore W1506724815C121608353 @default.
• W1506724815 hasConceptScore W1506724815C126322002 @default.
• W1506724815 hasConceptScore W1506724815C142724271 @default.
• W1506724815 hasConceptScore W1506724815C18903297 @default.
• W1506724815 hasConceptScore W1506724815C2775894508 @default.
• W1506724815 hasConceptScore W1506724815C2776235491 @default.
• W1506724815 hasConceptScore W1506724815C2777286243 @default.
• W1506724815 hasConceptScore W1506724815C2777550702 @default.
• W1506724815 hasConceptScore W1506724815C2779534503 @default.
• W1506724815 hasConceptScore W1506724815C2781340805 @default.
• W1506724815 hasConceptScore W1506724815C71924100 @default.
• W1506724815 hasConceptScore W1506724815C86803240 @default.
• W1506724815 hasIssue "7" @default.
• W1506724815 hasLocation W15067248151 @default.
• W1506724815 hasLocation W15067248152 @default.
• W1506724815 hasOpenAccess W1506724815 @default.
• W1506724815 hasPrimaryLocation W15067248151 @default.
• W1506724815 hasRelatedWork W1506724815 @default.
• W1506724815 hasRelatedWork W1997218965 @default.
• W1506724815 hasRelatedWork W2151135951 @default.
• W1506724815 hasRelatedWork W2155383658 @default.
• W1506724815 hasRelatedWork W2216606945 @default.
• W1506724815 hasRelatedWork W2400719740 @default.
• W1506724815 hasRelatedWork W2797386587 @default.
• W1506724815 hasRelatedWork W2952067578 @default.
• W1506724815 hasRelatedWork W3088615052 @default.
• W1506724815 hasRelatedWork W3195004279 @default.
• W1506724815 hasVolume "40" @default.
• W1506724815 isParatext "false" @default.

• next