FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1506869135> ?p ?o ?g. }

• W1506869135 endingPage "12678" @default.
• W1506869135 startingPage "12671" @default.
• W1506869135 abstract "Clonal expansion of antigen-specific lymphocytes is an important aspect of the immune response. Interleukin 2 (IL2) is largely responsible for the amplification of antigen-specific T cells. In this study, the changes in gene expression accompanying interleukin 2 stimulation of T cells are examined, using a cloned T helper lymphocyte line as a model system. To isolate cDNA clones of IL2-induced genes, a cDNA library was screened by differential hybridization. Twenty-one different cDNA clones were isolated by this method, comprising six glycolytic enzymes, vimentin, alpha-tubulin, beta-actin, gamma-actin, ERp99, elongation factor 2, ribosomal phosphoprotein P1, the DNA-binding protein dbpB/YB-1, as well as seven clones which do not correspond to any previously described sequences. These clones are used to study the time course of expression and the sensitivity to cycloheximide inhibition of IL2-induced mRNAs. In addition, the tissue specificity of the unidentified mRNAs is examined, and two of these are shown to be expressed at high levels in normal mouse brain, with much lower or undetectable levels in the other tissues tested. These cDNA clones will be useful in future studies to determine the molecular basis of IL2-induced gene expression." @default.
• W1506869135 created "2016-06-24" @default.
• W1506869135 creator A5042536378 @default.
• W1506869135 creator A5074196365 @default.
• W1506869135 creator A5077777322 @default.
• W1506869135 creator A5088560851 @default.
• W1506869135 date "1990-07-01" @default.
• W1506869135 modified "2023-09-28" @default.
• W1506869135 title "cDNA cloning and characterization of interleukin 2-induced genes in a cloned T helper lymphocyte." @default.
• W1506869135 cites W1479809193 @default.
• W1506869135 cites W1479896379 @default.
• W1506869135 cites W1550698494 @default.
• W1506869135 cites W1574327030 @default.
• W1506869135 cites W1620091220 @default.
• W1506869135 cites W1677703863 @default.
• W1506869135 cites W1953387593 @default.
• W1506869135 cites W1969809783 @default.
• W1506869135 cites W1979512488 @default.
• W1506869135 cites W1984767179 @default.
• W1506869135 cites W1989153321 @default.
• W1506869135 cites W1991157588 @default.
• W1506869135 cites W1993259001 @default.
• W1506869135 cites W1996668195 @default.
• W1506869135 cites W2000677160 @default.
• W1506869135 cites W2003186941 @default.
• W1506869135 cites W2005260875 @default.
• W1506869135 cites W2012913493 @default.
• W1506869135 cites W2014669590 @default.
• W1506869135 cites W2015292449 @default.
• W1506869135 cites W2019712287 @default.
• W1506869135 cites W2028158224 @default.
• W1506869135 cites W2030977214 @default.
• W1506869135 cites W2031590981 @default.
• W1506869135 cites W2034714974 @default.
• W1506869135 cites W2035731426 @default.
• W1506869135 cites W2042917826 @default.
• W1506869135 cites W2047043554 @default.
• W1506869135 cites W2052082365 @default.
• W1506869135 cites W2052537645 @default.
• W1506869135 cites W2060333964 @default.
• W1506869135 cites W2062241969 @default.
• W1506869135 cites W2064670731 @default.
• W1506869135 cites W2071250969 @default.
• W1506869135 cites W2074563618 @default.
• W1506869135 cites W2076892293 @default.
• W1506869135 cites W2077492124 @default.
• W1506869135 cites W2080410331 @default.
• W1506869135 cites W2090741624 @default.
• W1506869135 cites W2091239909 @default.
• W1506869135 cites W2095736624 @default.
• W1506869135 cites W2097128116 @default.
• W1506869135 cites W2122408922 @default.
• W1506869135 cites W2123824838 @default.
• W1506869135 cites W2155968662 @default.
• W1506869135 cites W2164515753 @default.
• W1506869135 cites W2167604659 @default.
• W1506869135 cites W2171460503 @default.
• W1506869135 cites W2224929038 @default.
• W1506869135 cites W236654392 @default.
• W1506869135 doi "https://doi.org/10.1016/s0021-9258(19)38396-6" @default.
• W1506869135 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2142689" @default.
• W1506869135 hasPublicationYear "1990" @default.
• W1506869135 type Work @default.
• W1506869135 sameAs 1506869135 @default.
• W1506869135 citedByCount "72" @default.
• W1506869135 countsByYear W15068691352012 @default.
• W1506869135 countsByYear W15068691352013 @default.
• W1506869135 countsByYear W15068691352014 @default.
• W1506869135 countsByYear W15068691352016 @default.
• W1506869135 countsByYear W15068691352017 @default.
• W1506869135 crossrefType "journal-article" @default.
• W1506869135 hasAuthorship W1506869135A5042536378 @default.
• W1506869135 hasAuthorship W1506869135A5074196365 @default.
• W1506869135 hasAuthorship W1506869135A5077777322 @default.
• W1506869135 hasAuthorship W1506869135A5088560851 @default.
• W1506869135 hasBestOaLocation W15068691351 @default.
• W1506869135 hasConcept C104317684 @default.
• W1506869135 hasConcept C121050878 @default.
• W1506869135 hasConcept C153911025 @default.
• W1506869135 hasConcept C159047783 @default.
• W1506869135 hasConcept C187882448 @default.
• W1506869135 hasConcept C19924922 @default.
• W1506869135 hasConcept C199360897 @default.
• W1506869135 hasConcept C41008148 @default.
• W1506869135 hasConcept C54355233 @default.
• W1506869135 hasConcept C86803240 @default.
• W1506869135 hasConceptScore W1506869135C104317684 @default.
• W1506869135 hasConceptScore W1506869135C121050878 @default.
• W1506869135 hasConceptScore W1506869135C153911025 @default.
• W1506869135 hasConceptScore W1506869135C159047783 @default.
• W1506869135 hasConceptScore W1506869135C187882448 @default.
• W1506869135 hasConceptScore W1506869135C19924922 @default.
• W1506869135 hasConceptScore W1506869135C199360897 @default.
• W1506869135 hasConceptScore W1506869135C41008148 @default.
• W1506869135 hasConceptScore W1506869135C54355233 @default.
• W1506869135 hasConceptScore W1506869135C86803240 @default.
• W1506869135 hasIssue "21" @default.
• W1506869135 hasLocation W15068691351 @default.

• next