Matches in SemOpenAlex for { <https://semopenalex.org/work/W1507159017> ?p ?o ?g. }
- W1507159017 endingPage "40" @default.
- W1507159017 startingPage "23" @default.
- W1507159017 abstract "We used fluorescence spectroscopy in an attempt to identify differences in the fibroblast cell membranes from individuals with Huntington's disease (HD), compared to those from normal individuals. Eight pairs of age- and sex-matched fibroblast cultures were examined, each using four different fluorescent probes. To maximize the possibility of finding a difference between the normal and HD cells fluorescence probes were selected which localize in different regions of the membrane. Also, these probes differed in their sensitivity to the surrounding environment. Procedures were developed for labeling of the fibroblasts while they were still attached to glass coverslips. All fluorescence measurements were done on attached cells, which were all found to be viable by staining with trypan blue. Both low (5-7) and high (11-13) passage cultures were examined since earlier reports indicated that normal and HD fibroblasts could be distinguished at low passage using a fluorescence method. Using these 16 cultures, and multiple determinations of the fluorescence emission spectra, anisotropies, and lifetimes, we found no significant difference between normal and HD fibroblasts. If such a difference exists, it appears to be too small for use as a diagnostic indicator for Huntington's disease." @default.
- W1507159017 created "2016-06-24" @default.
- W1507159017 creator A5049843236 @default.
- W1507159017 creator A5074798370 @default.
- W1507159017 date "1983-12-01" @default.
- W1507159017 modified "2023-09-25" @default.
- W1507159017 title "Evidence for normal fibroblast cell membranes from individuals with Huntington's disease" @default.
- W1507159017 cites W10036450 @default.
- W1507159017 cites W1508522114 @default.
- W1507159017 cites W1526385127 @default.
- W1507159017 cites W1571611410 @default.
- W1507159017 cites W1602158583 @default.
- W1507159017 cites W1965552027 @default.
- W1507159017 cites W1973355924 @default.
- W1507159017 cites W1980997064 @default.
- W1507159017 cites W1986995730 @default.
- W1507159017 cites W1987221264 @default.
- W1507159017 cites W1991079346 @default.
- W1507159017 cites W1994673901 @default.
- W1507159017 cites W2005506048 @default.
- W1507159017 cites W2015741258 @default.
- W1507159017 cites W2019663843 @default.
- W1507159017 cites W2022994075 @default.
- W1507159017 cites W2023313928 @default.
- W1507159017 cites W2024406171 @default.
- W1507159017 cites W2035028075 @default.
- W1507159017 cites W2036301724 @default.
- W1507159017 cites W2037975846 @default.
- W1507159017 cites W2038309413 @default.
- W1507159017 cites W2045742282 @default.
- W1507159017 cites W2046227562 @default.
- W1507159017 cites W2046618945 @default.
- W1507159017 cites W2046762347 @default.
- W1507159017 cites W2047113209 @default.
- W1507159017 cites W2050029239 @default.
- W1507159017 cites W2061308784 @default.
- W1507159017 cites W2062530685 @default.
- W1507159017 cites W2063295549 @default.
- W1507159017 cites W2067633620 @default.
- W1507159017 cites W2071930296 @default.
- W1507159017 cites W2074506394 @default.
- W1507159017 cites W2074693079 @default.
- W1507159017 cites W2076671354 @default.
- W1507159017 cites W2076773567 @default.
- W1507159017 cites W2078926179 @default.
- W1507159017 cites W2086275842 @default.
- W1507159017 cites W2087298783 @default.
- W1507159017 cites W2089683940 @default.
- W1507159017 cites W2094569563 @default.
- W1507159017 cites W2107952739 @default.
- W1507159017 cites W2132185229 @default.
- W1507159017 cites W2141731191 @default.
- W1507159017 cites W2159916641 @default.
- W1507159017 cites W2284982924 @default.
- W1507159017 cites W2411170196 @default.
- W1507159017 cites W2418133827 @default.
- W1507159017 cites W2475077654 @default.
- W1507159017 cites W3026571928 @default.
- W1507159017 cites W4246432387 @default.
- W1507159017 cites W4300519049 @default.
- W1507159017 doi "https://doi.org/10.1016/0022-510x(83)90187-9" @default.
- W1507159017 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6230415" @default.
- W1507159017 hasPublicationYear "1983" @default.
- W1507159017 type Work @default.
- W1507159017 sameAs 1507159017 @default.
- W1507159017 citedByCount "14" @default.
- W1507159017 crossrefType "journal-article" @default.
- W1507159017 hasAuthorship W1507159017A5049843236 @default.
- W1507159017 hasAuthorship W1507159017A5074798370 @default.
- W1507159017 hasConcept C121332964 @default.
- W1507159017 hasConcept C126322002 @default.
- W1507159017 hasConcept C142724271 @default.
- W1507159017 hasConcept C1491633281 @default.
- W1507159017 hasConcept C153911025 @default.
- W1507159017 hasConcept C185592680 @default.
- W1507159017 hasConcept C2778106830 @default.
- W1507159017 hasConcept C2779134260 @default.
- W1507159017 hasConcept C2780070996 @default.
- W1507159017 hasConcept C2780381497 @default.
- W1507159017 hasConcept C2780647506 @default.
- W1507159017 hasConcept C3018023364 @default.
- W1507159017 hasConcept C41625074 @default.
- W1507159017 hasConcept C54355233 @default.
- W1507159017 hasConcept C62520636 @default.
- W1507159017 hasConcept C71924100 @default.
- W1507159017 hasConcept C74864618 @default.
- W1507159017 hasConcept C81885089 @default.
- W1507159017 hasConcept C86803240 @default.
- W1507159017 hasConcept C91881484 @default.
- W1507159017 hasConceptScore W1507159017C121332964 @default.
- W1507159017 hasConceptScore W1507159017C126322002 @default.
- W1507159017 hasConceptScore W1507159017C142724271 @default.
- W1507159017 hasConceptScore W1507159017C1491633281 @default.
- W1507159017 hasConceptScore W1507159017C153911025 @default.
- W1507159017 hasConceptScore W1507159017C185592680 @default.
- W1507159017 hasConceptScore W1507159017C2778106830 @default.
- W1507159017 hasConceptScore W1507159017C2779134260 @default.
- W1507159017 hasConceptScore W1507159017C2780070996 @default.