Matches in SemOpenAlex for { <https://semopenalex.org/work/W1507215013> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W1507215013 endingPage "15176" @default.
- W1507215013 startingPage "15173" @default.
- W1507215013 abstract "Abstract N-Myristoyl and non-myristoyl peptides corresponding to the N terminus of p60src were used to examine whether N-myristoylation facilitates the binding of p60src to specific protein sites at the plasma membrane. We discovered high affinity protein acceptor sites (Kd = 2.7 nM) to a 15-amino acid N-myristoylated N-terminal p60src peptide in red cell membrane vesicles. Binding was not competed by the non-myristoylated analog of the peptide nor by shorter N-myristoyl src peptides and peptides homologous to the N terminus of other N-myristoylated proteins. Binding was not evident after treatment of vesicles with proteolytic enzymes. Raising the salt concentration of the buffer to 50 mM NaCl caused an apparent inhibition of binding. However, no significant effect of salt was observed on the off-rate of bound ligand under these conditions. The results indicate the existence of N-myristoyl-dependent p60src protein acceptor sites at or near the plasma membrane/skeleton interface of red cells which could be responsible for the localization of p60src to this region and may represent new regulatory components for p60src-mediated tyrosine kinase activity." @default.
- W1507215013 created "2016-06-24" @default.
- W1507215013 creator A5009710628 @default.
- W1507215013 creator A5062626303 @default.
- W1507215013 creator A5073341190 @default.
- W1507215013 date "1989-09-01" @default.
- W1507215013 modified "2023-09-30" @default.
- W1507215013 title "High affinity binding of an N-terminal myristoylated p60 peptide" @default.
- W1507215013 cites W1531422723 @default.
- W1507215013 cites W1897669544 @default.
- W1507215013 cites W1918682007 @default.
- W1507215013 cites W1971154723 @default.
- W1507215013 cites W1980646384 @default.
- W1507215013 cites W1998250646 @default.
- W1507215013 cites W2010002190 @default.
- W1507215013 cites W2016388741 @default.
- W1507215013 cites W2020357781 @default.
- W1507215013 cites W2028838986 @default.
- W1507215013 cites W2030017358 @default.
- W1507215013 cites W2043813981 @default.
- W1507215013 cites W2044311721 @default.
- W1507215013 cites W2052692052 @default.
- W1507215013 cites W2072651877 @default.
- W1507215013 cites W2079791947 @default.
- W1507215013 cites W2089123000 @default.
- W1507215013 cites W2100837269 @default.
- W1507215013 cites W2137105424 @default.
- W1507215013 cites W2143674123 @default.
- W1507215013 cites W2401692703 @default.
- W1507215013 doi "https://doi.org/10.1016/s0021-9258(19)84805-6" @default.
- W1507215013 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2504718" @default.
- W1507215013 hasPublicationYear "1989" @default.
- W1507215013 type Work @default.
- W1507215013 sameAs 1507215013 @default.
- W1507215013 citedByCount "33" @default.
- W1507215013 crossrefType "journal-article" @default.
- W1507215013 hasAuthorship W1507215013A5009710628 @default.
- W1507215013 hasAuthorship W1507215013A5062626303 @default.
- W1507215013 hasAuthorship W1507215013A5073341190 @default.
- W1507215013 hasBestOaLocation W15072150131 @default.
- W1507215013 hasConcept C185592680 @default.
- W1507215013 hasConcept C2779281246 @default.
- W1507215013 hasConcept C2779664074 @default.
- W1507215013 hasConcept C41008148 @default.
- W1507215013 hasConcept C55493867 @default.
- W1507215013 hasConcept C76155785 @default.
- W1507215013 hasConceptScore W1507215013C185592680 @default.
- W1507215013 hasConceptScore W1507215013C2779281246 @default.
- W1507215013 hasConceptScore W1507215013C2779664074 @default.
- W1507215013 hasConceptScore W1507215013C41008148 @default.
- W1507215013 hasConceptScore W1507215013C55493867 @default.
- W1507215013 hasConceptScore W1507215013C76155785 @default.
- W1507215013 hasIssue "26" @default.
- W1507215013 hasLocation W15072150131 @default.
- W1507215013 hasOpenAccess W1507215013 @default.
- W1507215013 hasPrimaryLocation W15072150131 @default.
- W1507215013 hasRelatedWork W1981944109 @default.
- W1507215013 hasRelatedWork W2039500468 @default.
- W1507215013 hasRelatedWork W2039608939 @default.
- W1507215013 hasRelatedWork W2073199546 @default.
- W1507215013 hasRelatedWork W2108725809 @default.
- W1507215013 hasRelatedWork W2254015490 @default.
- W1507215013 hasRelatedWork W2782497155 @default.
- W1507215013 hasRelatedWork W4244667361 @default.
- W1507215013 hasRelatedWork W4362500356 @default.
- W1507215013 hasRelatedWork W2054034248 @default.
- W1507215013 hasVolume "264" @default.
- W1507215013 isParatext "false" @default.
- W1507215013 isRetracted "false" @default.
- W1507215013 magId "1507215013" @default.
- W1507215013 workType "article" @default.