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- W1507522463 abstract "Amac: Oksidan ve antioksidan dengedeki bozukluklar talasemi ve orak hucreli anemi gibi hemoglobinopatilerde saptanmistir. Calismada duzenli olarak transfuzyon yapilan ve selasyon tedavisi alan 11 beta talasemi major hastasinda oksidan ve antioksidan ozellikler calisilmistir. Gerec ve yontem: Hastalarin laboratuar degerleri cinsiyet ve yaslari calisma grubuna uygun 10 saglikli cocuk ile karsilastirilmistir. Bulgular: Koruyucu bir antioksidan olan eritrosit superoksid dismutazi (ESOD) ve lipit peroksidasyonunun yikim urunu olan plazma malonildialdehid (MDA) duzeyleri calisma grubunda saglikli cocuklara gore yuksek bulunmustur. Serum vitamin E duzeyleri ise saglikli cocuklara gore dusuk bulunmustur. Sonuc: Talasemilerin patogenezinde demir yuklenmesi sonucu olusan artmis oksidatif yikim onemlidir. Ayrica vitamin E gibi yagda eriyen vitaminlerin yetersizligi sonucu olarak antioksidan durumun bozulmasi oksidatif yikimda artisa neden olur." @default.
- W1507522463 created "2016-06-24" @default.
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- W1507522463 date "2005-01-01" @default.
- W1507522463 modified "2023-09-23" @default.
- W1507522463 title "Oxidant and antioxidant status in beta thalassemia major patients" @default.
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- W1507522463 doi "https://doi.org/10.1501/ankara-4882" @default.
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