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• W1507654552 abstract "My doctoral thesis contributes to the understanding of gait, mobility, and falls in older people. Allpresented projects investigated the most prominent and sensitive markers for fall-related gait changes,that is gait velocity and gait variability. Based on the measurement of these spatio-temporal gaitparameters, particularly when using a change-sensitive dual task paradigm, it is possible to makeconclusions regarding walking, balance, activities of daily living, and falls in older people. Theresearch summarized in my doctoral thesis will help in the detection of early fall risk and modulation oftherapeutic interventions to improve gait and consequently reduce fall risk in older people.To identify modifiable fall risk factors, such as gait disorders, the GAITRite electronic walkway systemwas used for objective spatio-temporal gait analysis. The simplicity and feasibility of the administrationof single and dual task gait analysis make it a desirable clinical and research measurement tool. Gaitanalysis with walking as a single task condition alone is often insufficient to reveal underlying gaitdisorders present during everyday activities. However, measuring gait with a dual task paradigm candetect subtle gait deficits. Dual-tasking, walking while simultaneously performing an additional task,was used to assess the effects of divided attention on motor performance and gait control.The presented publications in this doctoral thesis investigated the association between gaitparameters and several hypothesized fall-related modalities: (a) Our first review article highlighted theassociation between gait disorders and falls, and how related motor and cognitive impairments can bedetected by measuring gait while dual-tasking. (b) A second review looked at how the dual taskparadigm can be used for gait assessment in older people and how spatio-temporal gait parametersare associated with increased fall risk. (c) Our systematic literature review provided evidence abouteffective fall prevention interventions (exercise, home modifications, footwear, and walking aids) toreduce the risk of falls in vulnerable older people. (d) To evaluate which exercise modalities areeffective in modifying risk factors for falls, we conducted an eight-week salsa intervention trial andmeasured the effect of dancing on static and dynamic balance, and leg muscle power in older people.(e) Besides exercise, inadequate nutritional intake is another modifiable risk factor for falls in olderpeople, and therefore our most recent cross-sectional study examined how serum 25-hydroxvitamin Dlevels are associated with functional mobility in older people assessed in a memory clinic. (c) Walkingaids are commonly prescribed for older people with a high risk of falls which is why we examined theinfluence of walking aids on spatio-temporal gait parameters in older people who used a cane, acrutch or a walker. (g) Finally, besides predominantly investigating fall risk factors for motor abilities,our prolonged and ongoing randomized, double-blind, and placebo-controlled intervention trialexplores the potential influence of ginkgo biloba on the cognitive domain relevant for dual-tasking inolder people with mild cognitive impairment." @default.
• W1507654552 created "2016-06-24" @default.
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• W1507654552 date "2012-01-01" @default.
• W1507654552 modified "2023-09-23" @default.
• W1507654552 title "Gait, mobility, and falls in older people" @default.
• W1507654552 doi "https://doi.org/10.5451/unibas-006142878" @default.
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