Matches in SemOpenAlex for { <https://semopenalex.org/work/W1507665611> ?p ?o ?g. }
- W1507665611 abstract "Recent years have witnessed an explosion of studies aimed at uncovering the mechanisms by which eukaryotic genes are regulated at the transcriptional level. Among the arsenal of analytical techniques employed toward this end, the method of in vivo footprinting represents a particularly powerful approach. This is because, in its ideal form, the method allows a rather precise assignment of the sequence locations in and around a given gene that are bound in vivo by trans-acting, potentially regulatory factors. This chapter reviews the development of the technical approach from an historical standpoint, catalogs and discusses some of the more useful probes of chromatin structure that have been applied in vivo, and provides a perspective on some of the more important mechanistic insights into the process of gene regulation that have been revealed by its judicious application." @default.
- W1507665611 created "2016-06-24" @default.
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- W1507665611 date "1997-01-01" @default.
- W1507665611 modified "2023-09-27" @default.
- W1507665611 title "A Perspective on in Vivo Footprinting" @default.
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- W1507665611 doi "https://doi.org/10.1016/s1569-2558(08)60280-5" @default.
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