FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1507853028> ?p ?o ?g. }

• W1507853028 endingPage "14337" @default.
• W1507853028 startingPage "14328" @default.
• W1507853028 abstract "The P1 ParB protein is required for active partition and thus stable inheritance of the plasmid prophage. ParB and the Escherichia coli protein integration host factor (IHF) participate in the assembly of a partition complex at the centromere-like site parS. In this report the role of IHF in the formation of the partition complex has been explored. First, ParB protein was purified for these studies, which revealed that ParB forms a dimer in solution. Next, the IHF binding site was mapped to a 29-base pair region within parS, including the sequence TAACTGACTGTTT (which differs from the IHF consensus in two positions). IHF induced a strong bend in the DNA at its binding site. Versions of parS which have lost or damaged the IHF binding site bound ParB with greatly reduced affinity in vitro and in vivo. Measurements of binding constants showed that IHF increased ParB affinity for the wild-type parS site by about 10,000-fold. Finally, DNA supercoiling improved ParB binding in the presence of IHF but not in its absence. These observations led to the proposal that IHF and superhelicity assist ParB by promoting its precise positioning at parS, a spatial arrangement that results in a high affinity of ParB for parS." @default.
• W1507853028 created "2016-06-24" @default.
• W1507853028 creator A5060040224 @default.
• W1507853028 date "1991-08-01" @default.
• W1507853028 modified "2023-10-02" @default.
• W1507853028 title "The P1 plasmid partition complex at parS. The influence of Escherichia coli integration host factor and of substrate topology" @default.
• W1507853028 cites W1489555985 @default.
• W1507853028 cites W1493003808 @default.
• W1507853028 cites W1525570188 @default.
• W1507853028 cites W1542851976 @default.
• W1507853028 cites W1560365186 @default.
• W1507853028 cites W1584328291 @default.
• W1507853028 cites W1590555359 @default.
• W1507853028 cites W164096579 @default.
• W1507853028 cites W1963658914 @default.
• W1507853028 cites W1964713595 @default.
• W1507853028 cites W1966312583 @default.
• W1507853028 cites W1966443347 @default.
• W1507853028 cites W1970258574 @default.
• W1507853028 cites W1973763076 @default.
• W1507853028 cites W1987734519 @default.
• W1507853028 cites W1989054182 @default.
• W1507853028 cites W1995675455 @default.
• W1507853028 cites W2006020163 @default.
• W1507853028 cites W2010964779 @default.
• W1507853028 cites W2011093920 @default.
• W1507853028 cites W2023364466 @default.
• W1507853028 cites W2038874225 @default.
• W1507853028 cites W2044060614 @default.
• W1507853028 cites W2051021996 @default.
• W1507853028 cites W2058940094 @default.
• W1507853028 cites W2070887270 @default.
• W1507853028 cites W2078930772 @default.
• W1507853028 cites W2082927796 @default.
• W1507853028 cites W2092712085 @default.
• W1507853028 cites W2094308587 @default.
• W1507853028 cites W2095611420 @default.
• W1507853028 cites W2099105015 @default.
• W1507853028 cites W2100837269 @default.
• W1507853028 cites W2119586900 @default.
• W1507853028 cites W2146930979 @default.
• W1507853028 cites W2170160869 @default.
• W1507853028 cites W288150766 @default.
• W1507853028 cites W4242306912 @default.
• W1507853028 cites W4293247451 @default.
• W1507853028 cites W4296765338 @default.
• W1507853028 cites W87477820 @default.
• W1507853028 doi "https://doi.org/10.1016/s0021-9258(18)98688-6" @default.
• W1507853028 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1860842" @default.
• W1507853028 hasPublicationYear "1991" @default.
• W1507853028 type Work @default.
• W1507853028 sameAs 1507853028 @default.
• W1507853028 citedByCount "72" @default.
• W1507853028 countsByYear W15078530282012 @default.
• W1507853028 countsByYear W15078530282013 @default.
• W1507853028 countsByYear W15078530282014 @default.
• W1507853028 countsByYear W15078530282015 @default.
• W1507853028 countsByYear W15078530282016 @default.
• W1507853028 countsByYear W15078530282019 @default.
• W1507853028 countsByYear W15078530282022 @default.
• W1507853028 countsByYear W15078530282023 @default.
• W1507853028 crossrefType "journal-article" @default.
• W1507853028 hasAuthorship W1507853028A5060040224 @default.
• W1507853028 hasBestOaLocation W15078530281 @default.
• W1507853028 hasConcept C104317684 @default.
• W1507853028 hasConcept C114614502 @default.
• W1507853028 hasConcept C126831891 @default.
• W1507853028 hasConcept C184720557 @default.
• W1507853028 hasConcept C185592680 @default.
• W1507853028 hasConcept C22744801 @default.
• W1507853028 hasConcept C33923547 @default.
• W1507853028 hasConcept C42812 @default.
• W1507853028 hasConcept C54355233 @default.
• W1507853028 hasConcept C547475151 @default.
• W1507853028 hasConcept C86803240 @default.
• W1507853028 hasConcept C89423630 @default.
• W1507853028 hasConceptScore W1507853028C104317684 @default.
• W1507853028 hasConceptScore W1507853028C114614502 @default.
• W1507853028 hasConceptScore W1507853028C126831891 @default.
• W1507853028 hasConceptScore W1507853028C184720557 @default.
• W1507853028 hasConceptScore W1507853028C185592680 @default.
• W1507853028 hasConceptScore W1507853028C22744801 @default.
• W1507853028 hasConceptScore W1507853028C33923547 @default.
• W1507853028 hasConceptScore W1507853028C42812 @default.
• W1507853028 hasConceptScore W1507853028C54355233 @default.
• W1507853028 hasConceptScore W1507853028C547475151 @default.
• W1507853028 hasConceptScore W1507853028C86803240 @default.
• W1507853028 hasConceptScore W1507853028C89423630 @default.
• W1507853028 hasIssue "22" @default.
• W1507853028 hasLocation W15078530281 @default.
• W1507853028 hasOpenAccess W1507853028 @default.
• W1507853028 hasPrimaryLocation W15078530281 @default.
• W1507853028 hasRelatedWork W1969249387 @default.
• W1507853028 hasRelatedWork W1985426194 @default.
• W1507853028 hasRelatedWork W2041543427 @default.
• W1507853028 hasRelatedWork W2066042007 @default.
• W1507853028 hasRelatedWork W2094563497 @default.
• W1507853028 hasRelatedWork W2135369330 @default.

• next