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• W1507885723 abstract "The relaxation mechanisms (inner sphere, second sphere, and outer sphere) governing the effect of MRI contrast agents are described. Two kinds of agents, i.e., paramagnetic Gd complexes and superparamagnetic iron oxide nanoparticles, are presented and their efficiency (relaxivity) is developed. Some typical nuclear magnetic relaxation dispersion (NMRD) profiles representing the longitudinal proton relaxivity versus the Larmor frequency are provided and discussed. The parameters governing relaxation enhancement are discussed: the rotational correlation time, the water residence time of the water bound to the Gd, the distance between coordinated water proton and the electron spins, the number of water molecules, the longitudinal and transverse relaxation times of the electrons, and the translational correlation time. The chemical structures of these contrast agents and some of their biological applications, such as apoptosis, inflammation, or cell targeting, are given." @default.
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• W1507885723 date "2009-03-15" @default.
• W1507885723 modified "2023-09-25" @default.
• W1507885723 title "Contrast Agents for MRI: Recent Advances" @default.
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• W1507885723 doi "https://doi.org/10.1002/9780470034590.emrstm1049" @default.
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