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- W1507939621 abstract "Cesarean scar pregnancy is a rare form of ectopic pregnancy. Patients have a high risk of bleeding which sometimes leads to hysterectomy, compromising the reproductive future. There is no consensus on the best method to treat this condition. Conservative treatment and surgery has been proposed in different situations and with different levels of success. To evaluate the efficacy of conservative management of Cesarean scar pregnancy treated with Methotrexate. The medical records of women with Cesarean scar pregnancy from July 2007 to January 2012 were reviewed. The study was performed in the Department of Obstetrics at the Federal University of São Paulo. The diagnosis was confirmed by transvaginal ultrasound and magnetic resonance imaging, showing an empty uterine cavity with a gestational sac at the level of the internal cervix os, covering the site of the previous c-section scar. We assessed the presence of morbidity; necessity for further intervention, the initial values of beta-hCG, interval of time for the levels of beta-hCG to became negative, and the period for the regression of the cesarean scar pregnancy at ultrasound. The clinical success was defined as preservation of uterus and future fertility. During this period, 5 cases of Cesarean scar pregnancy were referred to our institution. All patients were treated with systemic Methotrexate in multiple doses. Three patients with live embryo were also treated with local injection of Methotrexate. In all cases, maternal recovery was complete. The initial values of beta-hCG ranged from 4846 to 125489 mUI/mL. The interval of time for the levels of beta-hCG to become negative ranged from 43 to 75 days. Out of five women, one has become pregnant again, and has delivered successfully. Medical treatment with methotrexate is an alternative option for the treatment of patients with Cesarean scar pregnancy who desire to preserve the reproductive future." @default.
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- W1507939621 date "2012-09-01" @default.
- W1507939621 modified "2023-10-17" @default.
- W1507939621 title "P04.08: Cesarean scar pregnancy managed conservatively: case series" @default.
- W1507939621 doi "https://doi.org/10.1002/uog.11808" @default.
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