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- W1508049463 abstract "Intracellular simian virus 40 (SV40) chromatin was photoreacted with a 3H-labeled psoralen derivative, hydroxymethyltrimethylpsoralen (HMT), at 48 h postinfection. Psoralen compounds have been shown to readily penetrate intact cells and, in the presence of long-wavelength UV light, form covalent adducts to DNA, preferentially at regions unprotected by nucleosomes. The average distribution pattern of [3H]HMT on the SV40 genome was determined by specific activity measurements of the DNA fragments generated by HindIII plus HpaII or by AtuI restriction enzyme digestion. At levels of 1 to 10 [3H]HMT photoadducts per SV40 molecule, the radiolabel was found to be distributed nonrandomly. Comparison of the labeling pattern in vivo with that of purified SV40 DNA labeled in vitro revealed one major difference. A region of approximately 400 base pairs, located between 0.65 and 0.73 on the physical map, was preferentially labeled under in vivo conditions. This finding strongly suggests that the highly accessible region near the origin of replication, previously observed on isolated SV40 minichromosomes, exists on SV40 chromatin in vivo during a lytic infection." @default.
- W1508049463 created "2016-06-24" @default.
- W1508049463 creator A5036775671 @default.
- W1508049463 creator A5075143597 @default.
- W1508049463 date "1982-01-01" @default.
- W1508049463 modified "2023-09-25" @default.
- W1508049463 title "Mapping the in vivo arrangement of nucleosomes on simian virus 40 chromatin by the photoaddition of radioactive hydroxymethyltrimethylpsoralen" @default.
- W1508049463 cites W1530036925 @default.
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- W1508049463 cites W1602342183 @default.
- W1508049463 cites W1663451148 @default.
- W1508049463 cites W1763079413 @default.
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- W1508049463 doi "https://doi.org/10.1128/jvi.41.1.78-87.1982" @default.
- W1508049463 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/256727" @default.
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