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- W1508127180 abstract "Multiple myeloma is a malignant plasma cell disorder in which the proliferation of the ma‐ lignant plasma cells leads to anemia, infections, bone fractures, hypercalcemia and renal dysfunction [1]. Affecting approximately 32,000 people each year worldwide, with a median age of onset of approximately 68 years, it is the second most common hematological malig‐ nancy after non-Hodgkin’s lymphoma (NHL). Two major advances have occurred in the treatment of multiple myeloma in the last two decades: the introduction of high-dose che‐ motherapy with autologous stem cell transplantation (ASCT), and the development of active drugs with a novel mechanism of action (proteasome inhibition and immunomodulation). Both advances have led to significant improvements in overall survival in this disease." @default.
- W1508127180 created "2016-06-24" @default.
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- W1508127180 date "2013-02-13" @default.
- W1508127180 modified "2023-10-02" @default.
- W1508127180 title "Proteasome Inhibition and Hematopoietic Stem Cell Transplantation in Multiple Myeloma" @default.
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- W1508127180 doi "https://doi.org/10.5772/54117" @default.
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