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- W1508212096 abstract "This paper records detailed observations on the effect of administered corticosteroids, particularly aldosterone, on the Na and K content of the parotid saliva of the sheep. A dose response relation between intravenous administration of physiological amounts of aldosterone and salivary Na/K ratio was demonstrated in Na replete normal and in Na deficient adrenalectomized sheep. It has been shown that infused glucocorticoids at levels similar to those maximally secreted by the sheep's adrenals have little or no effect on the parotid salivary Na/K ratio, but infused aldosterone has equivalent effect of endogenous aldosterone. A striking difference was shown between the sensitivity to aldosterone of the parotid of Na replete and Na deficient sheep. Experiments on intravenous infusion of aldosterone show that the parotid of a 30 kg Na depleted sheep may respond to as little as 1–2 μ g/hr. The relevance of these findings to the physiological problems of adaptation of ruminant animals to stringent ecological conditions involving changes in feeding habits is discussed." @default.
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- W1508212096 date "1964-01-01" @default.
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- W1508212096 title "THE EFFECT OF ADRENAL CORTICAL STEROIDS ON PAROTID SALIVARY SECRETION" @default.
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- W1508212096 doi "https://doi.org/10.1016/b978-1-4832-2871-6.50023-0" @default.
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