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- W1508313 abstract "Abstract Alternaria mali and A. kikuchiana , the causal fungi of Alternaria leaf spot disease of apples and black spot disease of Japanese pears, produce host-specific toxins, named AM-toxin I, II and III and AK-toxin I and II, as the primary determinants of these diseases. These toxins were isolated as crystals and their structures were elucidated to be 1 , 2 and 3 in Fig. 1 and 9 and 10 in Fig. 3. The AM- and AK-toxins not only showed extremely potent toxic activity, but solutions of these toxins also induced the same necrotic symptoms only on the leaves of the host plants as those observed on inoculation with the spores of the causal fungi and caused almost instantaneous electrolyte loss from leaf tissues of susceptible cultivars. An early ultrastructural change in cells treated with the toxins appeared to be alternation of the plasma membrane. This indicates that AM- and AK-toxins play an important role in host recognition of A. mali and A. kikuchiana during the early stage of infection. The results of NMR conformation analyses of AM-toxins including synthesized analogs, 4, 6, 7 and 8 in Fig. 1, indicate that the ring conformation of the molecules is strongly related to expression of the toxic activity." @default.
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- W1508313 date "1983-01-01" @default.
- W1508313 modified "2023-09-27" @default.
- W1508313 title "CHEMICAL BASIS OF HOST RECOGNITION BY ALTERNARIA SPECIES" @default.
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- W1508313 doi "https://doi.org/10.1016/b978-0-08-029223-6.50015-x" @default.
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