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- W1508648934 abstract "Abstract Sand flies in the psychodid subfamily P hlebotominae carry important human pathogens in the trypanosomatid protozoan genus Leishmania ( C upolillo). Despite the fact that hundreds of sequences for this group are now publicly available, they constitute different sets of taxa and genetic markers. Integrating these data to construct a molecular phylogeny of the family is a significant bioinformatics challenge. We used sequences of eight markers obtained from freshly collected sand flies from E thiopia and combined them with over 1300 publicly available sequences, performing a combined analysis after generating single terminal sequences from ancestral reconstructions for some individual markers. The resulting phylogeny had 113 terminals and recovered P hlebotominae and certain species groups as monopheletic. Although the 20 outgroups in P sychodinae were recovered as a well‐resolved clade with bootstrap support for many internal clades, P hlebotominae was recovered as several lineages with unclear relationships among them. However, phlebotomines clustered by geographic region, the most notable being all the N ew W orld species except Brumptomyia ( G alati), which were recovered as monophyletic. Our phylogeny suggests a S ub‐ S aharan A frican or S outh A sian origin for the subfamily, which subsequently expanded to the north and west, and eventually to the N ew W orld. Supported species groups are often composed of widespread species with overlapping ranges. This result highlights the need for a large increase in the amount and diversity of molecular sequence data, and a broad selection of terminals, to test taxonomic hypotheses and examine speciation processes in this important group of flies." @default.
- W1508648934 created "2016-06-24" @default.
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- W1508648934 date "2015-07-29" @default.
- W1508648934 modified "2023-10-18" @default.
- W1508648934 title "A phylogeny of sand flies (<scp>D</scp>iptera: <scp>P</scp>sychodidae: <scp>P</scp>hlebotominae), using recent <scp>E</scp>thiopian collections and a broad selection of publicly available <scp>DNA</scp> sequence data" @default.
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- W1508648934 doi "https://doi.org/10.1111/syen.12135" @default.
- W1508648934 hasPublicationYear "2015" @default.
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