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• W1508990872 abstract "This chapter contains sections titled: Introduction Classification of Optimization Literature Discrete Structural Modifications Formation of Zwitterions Control of log P Attenuation of pKa Survey of Strategies Used to Diminish hERG Discrete Structural Modifications Formation of Zwitterions Control of log P Attenuation of pKa Summary and Analysis Summary of Optimization Literature Global Analysis of Reported Optimizations Summary and Recommendations Future Directions References" @default.
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• W1508990872 date "2008-01-23" @default.
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• W1508990872 title "Strategy and Tactics for hERG Optimizations" @default.
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• W1508990872 doi "https://doi.org/10.1002/9783527621460.ch18" @default.
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