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• W1509065852 abstract "Nutrition during pregnancy is important for women's health, pregnancy outcome, and infant growth and health. The aim of the present study was to investigate whether weekly supplementation with iron and vitamin A of pregnant women improves growth and health, as indicated by reduced morbidity and improved mental and psychomotor development, of their infants. At 18 weeks of pregnancy, women from 5 villages were randomly assigned on an individual basis to supervised, double-masked supplementation once weekly from enrolment until delivery. Supplementation comprised 120 mg iron as Fe 2 SO 4 and 500μg folic acid with (n =121) or without (n=122) 4800 RE vitamin A. Pregnant women participating in the ongoing national iron supplementation programme and receiving iron/folic acid tablets through medical services were recruited at the same time from 4 neighbouring villages ('daily' group, n= 123). Compliance with iron tablet intake in this group was expected to be very low. Newborn infants were followed up at least until 1 year of age.At 4 months of age, infants in the weekly vitamin A plus iron group had significantly higher serum retinol concentrations than infants in the weekly iron group. However, in all groups >70% of the infants had serum retinol concentrations 18 weeks of pregnancy, housing, and postnatal variables such as intake of certain food groups and morbidity were predictors of growth and nutritional status of infants at 12 months of age. In conclusion, vitamin A supplementation in concurrence of iron supplementation of pregnant women does not improve growth or health of their infants. However, it improved vitamin A status of their infants at 4 months of age. Considering the association between growth and vitamin A status, and the high prevalence of serum retinol levels <0.70μmol/L, vitamin A intake during infancy may need to be increased. However, in order to optimise nutritional status and growth of infants the whole life cycle should be considered." @default.
• W1509065852 created "2016-06-24" @default.
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• W1509065852 date "2001-01-01" @default.
• W1509065852 modified "2023-09-26" @default.
• W1509065852 title "The role of maternal nutrition in growth and health of Indonesian infants: a focus on vitamin A and iron" @default.
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