Matches in SemOpenAlex for { <https://semopenalex.org/work/W1509146233> ?p ?o ?g. }
Showing items 1 to 51 of
51
with 100 items per page.
- W1509146233 abstract "This dissertation utilized electrospray ion mobility mass spectrometry (ESI-IMS-MS) to develop methods necessary for the separation of chiral compounds of forensic interest. The compounds separated included ephedrines and pseudoephedrines, that occur as impurities in confiscated amphetamine type substances (ATS) in an effort to determine the origin of these substances. The ESI-IMS-MS technique proved to be faster and more cost effective than traditional chromatographic methods currently used to conduct chiral separations such as gas and liquid chromatography. Both mass spectrometric and computational analysis revealed the separation mechanism of these chiral interactions allowing for further development to separate other chiral compounds by IMS. Successful separation of chiral compounds was achieved utilizing a variety of modifiers injected into the IMS drift tube. It was found that the modifiers themselves did not need to be chiral in nature and that achiral modifiers were sufficient in performing the required separations. The ESI-IMS-MS technique was also used to detect thermally labile compounds which are commonly found in explosive substances. The methods developed provided mass spectrometric identification of the type of ionic species being detected from explosive analytes as well as the appropriate solvent that enhances detection of these analytes in either the negative or positive ion mode. An application of the developed technique was applied to the analysis of a variety of low explosive smokeless powder samples. It was found that the developed ESI-IMS-MS technique not only detected the components of the smokeless powders, but also provided data that allowed the classification of the analyzed smokeless powders by manufacturer or make." @default.
- W1509146233 created "2016-06-24" @default.
- W1509146233 creator A5064338947 @default.
- W1509146233 date "2017-11-13" @default.
- W1509146233 modified "2023-09-23" @default.
- W1509146233 title "The Utilization of Chiral Ion Mobility Spectrometry for the Detection of Enantiomeric Mixtures and Thermally Labile Compounds" @default.
- W1509146233 doi "https://doi.org/10.25148/etd.fi13120421" @default.
- W1509146233 hasPublicationYear "2017" @default.
- W1509146233 type Work @default.
- W1509146233 sameAs 1509146233 @default.
- W1509146233 citedByCount "0" @default.
- W1509146233 crossrefType "dissertation" @default.
- W1509146233 hasAuthorship W1509146233A5064338947 @default.
- W1509146233 hasBestOaLocation W15091462331 @default.
- W1509146233 hasConcept C10390740 @default.
- W1509146233 hasConcept C15213710 @default.
- W1509146233 hasConcept C154238967 @default.
- W1509146233 hasConcept C162356407 @default.
- W1509146233 hasConcept C178790620 @default.
- W1509146233 hasConcept C185592680 @default.
- W1509146233 hasConcept C194451485 @default.
- W1509146233 hasConcept C40684141 @default.
- W1509146233 hasConcept C43617362 @default.
- W1509146233 hasConcept C486523 @default.
- W1509146233 hasConceptScore W1509146233C10390740 @default.
- W1509146233 hasConceptScore W1509146233C15213710 @default.
- W1509146233 hasConceptScore W1509146233C154238967 @default.
- W1509146233 hasConceptScore W1509146233C162356407 @default.
- W1509146233 hasConceptScore W1509146233C178790620 @default.
- W1509146233 hasConceptScore W1509146233C185592680 @default.
- W1509146233 hasConceptScore W1509146233C194451485 @default.
- W1509146233 hasConceptScore W1509146233C40684141 @default.
- W1509146233 hasConceptScore W1509146233C43617362 @default.
- W1509146233 hasConceptScore W1509146233C486523 @default.
- W1509146233 hasLocation W15091462331 @default.
- W1509146233 hasOpenAccess W1509146233 @default.
- W1509146233 hasPrimaryLocation W15091462331 @default.
- W1509146233 hasRelatedWork W1965595086 @default.
- W1509146233 hasRelatedWork W1982350335 @default.
- W1509146233 hasRelatedWork W2007802584 @default.
- W1509146233 hasRelatedWork W2023703104 @default.
- W1509146233 hasRelatedWork W2050011283 @default.
- W1509146233 hasRelatedWork W2142798374 @default.
- W1509146233 hasRelatedWork W2356672189 @default.
- W1509146233 hasRelatedWork W4306385886 @default.
- W1509146233 hasRelatedWork W4318586533 @default.
- W1509146233 hasRelatedWork W2525526490 @default.
- W1509146233 isParatext "false" @default.
- W1509146233 isRetracted "false" @default.
- W1509146233 magId "1509146233" @default.
- W1509146233 workType "dissertation" @default.