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- W1509146251 endingPage "e21" @default.
- W1509146251 startingPage "e6" @default.
- W1509146251 abstract "Approximately half of patients with heart failure (HF) have a preserved ejection fraction (HFpEF). Morbidity and mortality are similar to HF with reduced EF (HFrEF), yet therapies with unequivocal benefit in HFrEF have not been shown to be effective in HFpEF. Recent studies have shown that the pathophysiology of HFpEF, initially believed to be due principally to diastolic dysfunction, is more complex. Appreciation of this complexity has shed new light into how HFpEF patients might respond to traditional HF treatments, while also suggesting new applications for novel therapies and strategies. In this review, we shall briefly review the pathophysiologic mechanisms in HFpEF, currently available clinical trial data, and finally explore new investigational therapies that are being developed and tested in ongoing and forthcoming trials." @default.
- W1509146251 created "2016-06-24" @default.
- W1509146251 creator A5019711498 @default.
- W1509146251 creator A5030461468 @default.
- W1509146251 date "2010-03-29" @default.
- W1509146251 modified "2023-09-26" @default.
- W1509146251 title "Heart Failure with Preserved Ejection Fraction: Pathophysiology and Emerging Therapies" @default.
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