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• W1509347385 startingPage "1808" @default.
• W1509347385 abstract "Given its metastatic potential and high incidence, cutaneous squamous cell carcinoma of the head and neck (SCCHN) has significant morbidity and mortality.We conducted a retrospective review of prospectively collected data for 113 consecutive patients with nodal metastatic cutaneous SCCHN treated surgically with curative intent in a regional center. Survival curves were generated by the Kaplan-Meier method.Five-year overall survival (OS), disease-specific survival (DSS), and disease-free survival (DFS) were 80%, 83%, and 75%, respectively. Twenty-six patients (23%) relapsed, with 92% of relapses occurring within 2 years of surgery. Immunosuppression (p = .008) and N classification (p = .043) predicted decreased DFS on univariate analysis. On multivariate analysis, only immunosuppression independently predicted DFS (p = .034).This study validates the current N classification system, supports the adverse effect of immunosuppression, and suggests that intense follow-up for 2 years postsurgery is warranted. Survival at this regional center is comparable to that achieved at metropolitan tertiary cancer centers." @default.
• W1509347385 created "2016-06-24" @default.
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• W1509347385 date "2015-01-27" @default.
• W1509347385 modified "2023-10-06" @default.
• W1509347385 title "Outcomes of nodal metastatic cutaneous squamous cell carcinoma of the head and neck treated in a regional center" @default.
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• W1509347385 doi "https://doi.org/10.1002/hed.23843" @default.
• W1509347385 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24995842" @default.
• W1509347385 hasPublicationYear "2015" @default.
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