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- W1509394695 abstract "Background The cost‐effectiveness of the donor health questionnaire ( DHQ ) as a tool to assess donor eligibility has not been quantified. This study focused on cost‐effectiveness of the DHQ in preventing transfusion‐transmitted infections ( TTI s). Study Design and Methods Data on whole blood donor eligibility assessments in the N etherlands in 2008 to 2010 were analyzed. Based on test results and epidemiologic data on TTIs , the number of donor visits in their window phase was calculated. Subsequently, the incremental cost‐effectiveness ratio ( ICER ) of the DHQ was calculated. Results The overall annual deferral rate in the study period was 9.6% (9.3%‐10.0%). The annual deferral rate for TTI risk was 0.86% (0.82%‐0.89%). Taking into account the number of self‐deferrals, deferral rate for TTI risk in all donors was 1.90% (1.81%‐2.02%). The calculated annual numbers of prevented cases of TTI were hepatitis B , 0.142; hepatitis C , 0.010; human immunodeficiency virus, 0.016; and syphilis, 0.135. The annual costs for TTI risk–related eligibility assessments, deferrals, and substitutions were €84,807 (€55,193‐€123,811) for the blood establishment ( BE ) and €90,501 (€46,965‐€159,571) for deferred donors. Annual savings were €991 (€276‐€2325), while annual quality‐adjusted life‐years ( QALYs ) gained were 0.120 (0.059‐0.226). Hence, the ICER for the DHQ on preventing TTI s was €696,744 (€315,422‐€1,611,681) for BE costs only and €1,449,055 (€669,439‐€3,145,961) including costs for deferred donors. Conclusion The DHQ enhances self‐selection and should not be abandoned. However, the DHQ is not a cost‐effective tool for further reducing TTI s. The high costs per case prevented and the small number of QALY s gained argue against maintaining deferral policy through the DHQ at the current level." @default.
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- W1509394695 date "2013-07-25" @default.
- W1509394695 modified "2023-10-18" @default.
- W1509394695 title "Cost‐effectiveness of questionnaires in preventing transfusion‐transmitted infections" @default.
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- W1509394695 doi "https://doi.org/10.1111/trf.12349" @default.
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