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- W150940672 abstract "The presence of a testosterone-binding globulin, called sex steroid-binding plasma protein (SBP), in plasma has been reported. It was found that the testosterone-binding capacities (TBC) of various types of plasma differ from each other. The capacity is lowest in plasma of men and post-menopausal women, slightly higher in menstruating women and high in pregnant subjects. In oestrogen-treated subjects, high TBC has been found. These results suggested that oestrogens play an important role in this increase. In a number of methods presented for the determination of testosterone in female plasma, based on the principle of competitive protein-binding, late pregnancy plasma is used as the source of SBP. The plasma is diluted to minimize the nonspecific binding of testosterone by albumin and to obtain a standard curve in a range adequate for the determination of testosterone in plasma samples. Oestrogen excretion is higher in twin than in single pregnancies. Therefore, the TBC was determined in twin and single pregnancies and found it higher in the former." @default.
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- W150940672 date "1971-01-01" @default.
- W150940672 modified "2023-09-24" @default.
- W150940672 title "Plasma Testosterone Binding Capacity and Oestrogen Excretion in Normal and Pathological Pregnancies" @default.
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- W150940672 doi "https://doi.org/10.1016/b978-0-08-017573-7.50019-6" @default.
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