Matches in SemOpenAlex for { <https://semopenalex.org/work/W1509818> ?p ?o ?g. }
- W1509818 endingPage "198" @default.
- W1509818 startingPage "183" @default.
- W1509818 abstract "Osteolytic bone disease affects more than 80% of multiple myeloma (MM) patients with a negative impact on both quality of life and overall survival. The pathogenesis of osteolytic disease resides in increased osteoclast (OC) activation along with osteoblast (OB) inhibition resulting in altered bone remodeling. OC number and activity in MM are enhanced mainly via cytokine deregulation within the bone marrow (BM) milieu and an imbalance of the OC/OB axis. Several novel agents are currently under investigation for their positive effect on bone remodeling via OC inhibition or OB activation. In addition to restoring bone remodeling, these drugs may inhibit tumor growth in vivo. Therefore, targeting bone disease is a promising therapeutic strategy not only with the goal of alleviating morbidity from bone disease but also resultant anti-tumor activity." @default.
- W1509818 created "2016-06-24" @default.
- W1509818 creator A5052048627 @default.
- W1509818 creator A5090686439 @default.
- W1509818 date "2010-01-01" @default.
- W1509818 modified "2023-09-26" @default.
- W1509818 title "Osteoclast Activation in Multiple Myeloma" @default.
- W1509818 cites W1520422891 @default.
- W1509818 cites W1528751727 @default.
- W1509818 cites W1925814566 @default.
- W1509818 cites W1964328292 @default.
- W1509818 cites W1972201331 @default.
- W1509818 cites W1975825361 @default.
- W1509818 cites W1984068295 @default.
- W1509818 cites W1985919561 @default.
- W1509818 cites W1986310612 @default.
- W1509818 cites W1992422220 @default.
- W1509818 cites W1999077925 @default.
- W1509818 cites W2005360870 @default.
- W1509818 cites W2006778528 @default.
- W1509818 cites W2009140393 @default.
- W1509818 cites W2009275473 @default.
- W1509818 cites W2010547317 @default.
- W1509818 cites W2010552629 @default.
- W1509818 cites W2011926580 @default.
- W1509818 cites W2013187395 @default.
- W1509818 cites W2017682198 @default.
- W1509818 cites W2022154453 @default.
- W1509818 cites W2022292514 @default.
- W1509818 cites W2024299200 @default.
- W1509818 cites W2026387061 @default.
- W1509818 cites W2029720151 @default.
- W1509818 cites W2030504185 @default.
- W1509818 cites W2031284766 @default.
- W1509818 cites W2037927763 @default.
- W1509818 cites W2038063884 @default.
- W1509818 cites W2038329170 @default.
- W1509818 cites W2039215669 @default.
- W1509818 cites W2039670622 @default.
- W1509818 cites W2043295936 @default.
- W1509818 cites W2044794329 @default.
- W1509818 cites W2044835347 @default.
- W1509818 cites W2047647041 @default.
- W1509818 cites W2048709843 @default.
- W1509818 cites W2048994674 @default.
- W1509818 cites W2058914749 @default.
- W1509818 cites W2062809449 @default.
- W1509818 cites W2062972466 @default.
- W1509818 cites W2064200002 @default.
- W1509818 cites W2066000727 @default.
- W1509818 cites W2066329342 @default.
- W1509818 cites W2066936999 @default.
- W1509818 cites W2073927082 @default.
- W1509818 cites W2074174622 @default.
- W1509818 cites W2078400068 @default.
- W1509818 cites W2078493291 @default.
- W1509818 cites W2078671054 @default.
- W1509818 cites W2082529445 @default.
- W1509818 cites W2091231975 @default.
- W1509818 cites W2093921289 @default.
- W1509818 cites W2102969047 @default.
- W1509818 cites W2103904089 @default.
- W1509818 cites W2119810076 @default.
- W1509818 cites W2122473686 @default.
- W1509818 cites W2126120941 @default.
- W1509818 cites W2135892640 @default.
- W1509818 cites W2140017817 @default.
- W1509818 cites W2140353133 @default.
- W1509818 cites W2142149038 @default.
- W1509818 cites W2148096512 @default.
- W1509818 cites W2151788901 @default.
- W1509818 cites W2152387543 @default.
- W1509818 cites W2155061120 @default.
- W1509818 cites W2155910125 @default.
- W1509818 cites W2159860846 @default.
- W1509818 cites W2164174012 @default.
- W1509818 cites W2165326697 @default.
- W1509818 cites W2168307206 @default.
- W1509818 cites W2169802771 @default.
- W1509818 cites W2325285113 @default.
- W1509818 cites W2325302070 @default.
- W1509818 cites W2585578807 @default.
- W1509818 cites W4241997693 @default.
- W1509818 cites W4245752982 @default.
- W1509818 cites W4256655531 @default.
- W1509818 doi "https://doi.org/10.1007/978-1-60761-554-5_10" @default.
- W1509818 hasPublicationYear "2010" @default.
- W1509818 type Work @default.
- W1509818 sameAs 1509818 @default.
- W1509818 citedByCount "1" @default.
- W1509818 countsByYear W15098182012 @default.
- W1509818 crossrefType "book-chapter" @default.
- W1509818 hasAuthorship W1509818A5052048627 @default.
- W1509818 hasAuthorship W1509818A5090686439 @default.
- W1509818 hasConcept C126322002 @default.
- W1509818 hasConcept C150903083 @default.
- W1509818 hasConcept C170033053 @default.
- W1509818 hasConcept C170493617 @default.