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• W1510236821 abstract "Article1 May 1932The Significance of Lymphatic Tissue and Adenoma-Like Areas in the Thyroid GlandL. R. HIMMELBERGER, Ph.D.L. R. HIMMELBERGER, Ph.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-5-11-1404 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptWhile the terms Graves' disease, Basedow's disease and exophthalmic goiter are purely clinical expressions and their use in pathological connections perhaps questionable, no suitable pathological term exists that is descriptive of the changes seen in the thyroid gland in this disease. Parenchymatous hypertrophy and hyperplasia have been used quite properly but these expressions do not describe the most important changes seen, as we hope to show. The present clinical tendency to consider toxic adenoma as a condition separate from Graves' or Basedow's disease also lends confusion to a pathological understanding of the process in the thyroid gland.The association of...References1 HANSEMANN D: Schilddrüse und Thymus bei der Basedow'schen Krankheit, Berl. klin. Wchnschr., 1905, xlii, No. 44a, 65-66. Google Scholar2 CAPELLE : Beziehungen des Thymus zum Morbus Basedowii, Deutsch. med. Wchnschr., 1911, xxxvii, 1771. Über die Beziehungen der Thymus zum Morbus Basedow, Bruns' Beiträge zur klin. Chir., 1908, lviii, 353-393. Google Scholar3 CAPELLEBAYER WR: Thymektomie bei Morbus Basedow. Ein Beitrag für die Beziehungen der Thymus zur Basedow'schen Krankheit, Bruns' Beiträge zur klin. Chir., 1911, lxii, 214-238. Google Scholar4 BIRCHER E: Zur experimentellen Erzeugung des Morbus Basedowii, Zentralbl. f. Chir., 1912, xxxix, 138-140. Google Scholar5 PETTAVEL CA: Beitrag zum pathologischen Anatomie des Morbus Basedowii, Deutsch. Ztschr. f. Chir., 1912, cxvi, 488-542. Weiterer Beitrag zur pathologischen Anatomie des Morbus Basedowii, Mitt. a. d. Grenzgeb. d. Med. u. Chir., 1914, xxvii, 693-749. CrossrefGoogle Scholar6 MATTI H: Die Beziehungen der Thymus zum Morbus Basedowii, Berl. klin. Wchnschr., 1914, li, No. 28, 1310-1316., No. 29, 1365-1370. Über die Kombination von Morbus Basedowii mit Thymushyperplasie, Deutsch. Ztschr. f. Chir., 1912, cxvi, 1165-1167. Google Scholar7 RAUTMANN H: Pathologisch-anatomische Untersuchungen über die Basedowsche Krankheit, Mitt. a. d. Grenzgeb. d. Med. u. Chir., 1915, xxviii, 489-618. Google Scholar8 PETTAVEL CA: Weiterer Beitrag zur pathologischen Anatomie des Morbus Basedowii, Mitt. a. d. Grenzgeb. d. Med. u. Chir., 1914, xxvii, 693-749. Google Scholar9 KLOSE H: Die pathologisch-anatomischen Grundlagen der Basedow'schen Krankheit, Beitr. z. klin. Chir., 1916, cii, 1-109. Google Scholar10 MCCALLUM WG: A textbook of pathology, 1928, W. B. Saunders Co., Philadelphia. Google Scholar11 ASCHOFF S: Lectures on pathology, 1924, Paul B. Hoeber, New York. Google Scholar12 SAGER WW: Exophthalmic goiter; pathologic change as a result of the administration of iodine (Lugol's solution), Arch. Surg., 1927, xv, No. 6, 878-894. CrossrefGoogle Scholar13 RIENHOFF WF: Involutional or regressive changes in the thyroid gland in cases of exophthalmic goiter; and their relation to origin of certain of the so-called adenomas, Arch. Surg., 1926, xiii, 391-425. CrossrefGoogle Scholar14 BRODERS : Personal communication. Google Scholar15 MENNEJOYCEVON HUNGEN FBTMAP: Thyroid disturbances, clinicopathologic study of three hundred instances, Arch. Surg., 1926, xiii, No. 3, 329-342. CrossrefGoogle Scholar16 WARTHIN AS: The constitutional entity of exophthalmic goiter and the so-called toxic adenoma, Ann. Int. Med., 1928, ii, 553-570. Pathology of goiter, Proc. Inter-state Post. Grad. Med. Assoc., N. Am., (1929), 1930, v. 383-385. Google Scholar17 ELOVZIN M: Concerning presence of lymphocytes in thyroid gland, Jr. Detroit Coll. Med. and Surg., 1930, i, 72-82. Google Scholar18 CLARKEBLACK NEI: Postoperative results in toxic goiter, Arch. Int. Med., 1930, xlvi, 266-282. CrossrefGoogle Scholar19 SIMPSON WM: Graves' constitution (Warthin), Am. Jr., Surg., 1929, New series vii, No. I, 22-26. CrossrefGoogle Scholar20 HELLWIG CA: Graves' constitution (Warthin), Surg. Gynec. and Obst., 1931, lii, 43-51. Google Scholar21 MARINE D: The thyroid, parathyroids and thymus, special cytology, (E. V. Cowdry), 1928, i, 549-620, Paul B. Hoeber, New York. Google Scholar22 WILLIAMSONPEARCE GSIH: The structure of the thyroid organ in man, Jr. Path. and Bact., 1923, xxvi, 459-469. CrossrefGoogle Scholar23 RIENHOFF WF: Gross and microscopic structure of the thyroid gland in man, Arch. Surg., 1929, xix, 986-1036. CrossrefGoogle Scholar24 MURRAY IM: The thyroid gland in the full-term foetus and in the newly born infant, Brit. Med. Jr., 1927, i, 5-8. CrossrefGoogle Scholar25 HIMMELBERGER LR: Status lymphaticus,, Jr. Mich. Med. Soc., 1928, xxvii, 337-339. Google Scholar26 CROTTI A: Thyroid and thymus, 1922, Lea and Febiger, Philadelphia. Google Scholar27 JACKSON SS: Iodine as a cause of hyperthyroidism, Jr.-Lan., 1924, xliv, 324-328. Google Scholar28 EWING J: Neoplastic diseases, 1928, W. B. Saunders Co., Philadelphia. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Flint, Michigan*From the Laboratory of Hurley Hospital, Flint, Michigan.**Thesis presented to the Faculty of Michigan State College, in partial fulfillment of the requirements for the degree of Doctor of Philosophy.†Received for publication, April 15, 1931. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byLymphatic tissue and regressive structure, with particular reference to degeneration of glands 1 May 1932Volume 5, Issue 11Page: 1404-1420KeywordsAdenomasLymphoid tissueResearch laboratoriesThyroid ePublished: 1 December 2008 Issue Published: 1 May 1932 PDF downloadLoading ..." @default.
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