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- W1510386906 abstract "The immunogenicity of an acellular pertussis vaccine containing genetically detoxified pertussis toxin, filamentous haemoagglutinin and pertactin was studied in 12 children [median age: 45 (6–107) months] with perinatal human immunodeficiency virus-type 1 (HIV-1) infection. Antibody response to all antigens was observed in six cases and another children 3 reacted to two or one antigen(s), but titres were lower than those from healthy controls. Antibody titre fold-rise correlated with preimmunization CD4-positive cell counts. Significant titres were still detectable 4 months after the third dose. The acellular vaccine is immunogenic in a portion of children with perinatal HIV-1 infection but early vaccination might be more effective, taking advantage of still adequate CD4-positive cell numbers." @default.
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- W1510386906 date "1997-08-01" @default.
- W1510386906 modified "2023-09-27" @default.
- W1510386906 title "Acellular pertussis vaccine in children with perinatal human immunodeficiency virus-type 1 infection" @default.
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- W1510386906 doi "https://doi.org/10.1016/s0264-410x(97)00024-8" @default.
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