Matches in SemOpenAlex for { <https://semopenalex.org/work/W1510444590> ?p ?o ?g. }
- W1510444590 endingPage "433" @default.
- W1510444590 startingPage "426" @default.
- W1510444590 abstract "Cytokine receptors expressed by CD4(+) FoxP3(+) regulatory T cells (Treg cells) not only serve as a phenotypic marker for the identification of this important population of immunosuppressive cells, they also promote the function of Treg cells. CD25, the α-chain of interleukin-2 receptor, is a prototype of such a receptor, which enables Treg cells to be activated by interleukin-2. We and others have found that tumour necrosis factor receptor type 2 (TNFR2) is another important cytokine receptor preferentially expressed by Treg cells with important phenotypic and functional roles. TNFR2 is preferentially expressed by highly functional human and mouse Treg cells, and mediates the activating effect of TNF on Treg cells. We review here the studies of the regulation of expression of TNFR2 on functional Treg cells as well as on CD4(+) FoxP3(-) effector T cells (Teff cells). We document the critical role of this receptor in the activation, proliferative expansion and survival of Treg cells. The contribution of TNFR2 expression on Treg and Teff cells to the beneficial and detrimental effects of anti-TNF treatment in autoimmune disorders will also be discussed." @default.
- W1510444590 created "2016-06-24" @default.
- W1510444590 creator A5042240287 @default.
- W1510444590 creator A5059944329 @default.
- W1510444590 date "2011-06-02" @default.
- W1510444590 modified "2023-10-06" @default.
- W1510444590 title "The phenotypic and functional consequences of tumour necrosis factor receptor type 2 expression on CD4+ FoxP3+ regulatory T cells" @default.
- W1510444590 cites W1499979791 @default.
- W1510444590 cites W1508779235 @default.
- W1510444590 cites W1509596990 @default.
- W1510444590 cites W1523595999 @default.
- W1510444590 cites W1557037837 @default.
- W1510444590 cites W1599910722 @default.
- W1510444590 cites W1600348345 @default.
- W1510444590 cites W1617336701 @default.
- W1510444590 cites W1619186743 @default.
- W1510444590 cites W1678438229 @default.
- W1510444590 cites W1885103044 @default.
- W1510444590 cites W1971370578 @default.
- W1510444590 cites W1971782694 @default.
- W1510444590 cites W1977762182 @default.
- W1510444590 cites W1979966334 @default.
- W1510444590 cites W1980690619 @default.
- W1510444590 cites W1981306008 @default.
- W1510444590 cites W1984113136 @default.
- W1510444590 cites W1990227965 @default.
- W1510444590 cites W1995346461 @default.
- W1510444590 cites W1998254244 @default.
- W1510444590 cites W2002344508 @default.
- W1510444590 cites W2004708987 @default.
- W1510444590 cites W2008870899 @default.
- W1510444590 cites W2013136814 @default.
- W1510444590 cites W2014553274 @default.
- W1510444590 cites W2029993898 @default.
- W1510444590 cites W2036383793 @default.
- W1510444590 cites W2048747915 @default.
- W1510444590 cites W2061071534 @default.
- W1510444590 cites W2067024450 @default.
- W1510444590 cites W2069640685 @default.
- W1510444590 cites W2086255604 @default.
- W1510444590 cites W2089840760 @default.
- W1510444590 cites W2091520971 @default.
- W1510444590 cites W2093383759 @default.
- W1510444590 cites W2094835614 @default.
- W1510444590 cites W2097057955 @default.
- W1510444590 cites W2103180268 @default.
- W1510444590 cites W2116725410 @default.
- W1510444590 cites W2118268169 @default.
- W1510444590 cites W2118443170 @default.
- W1510444590 cites W2119991694 @default.
- W1510444590 cites W2123249923 @default.
- W1510444590 cites W2135567354 @default.
- W1510444590 cites W2138702511 @default.
- W1510444590 cites W2140104241 @default.
- W1510444590 cites W2149626878 @default.
- W1510444590 cites W2153045866 @default.
- W1510444590 cites W2162124617 @default.
- W1510444590 cites W2168707849 @default.
- W1510444590 doi "https://doi.org/10.1111/j.1365-2567.2011.03460.x" @default.
- W1510444590 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3143354" @default.
- W1510444590 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21631498" @default.
- W1510444590 hasPublicationYear "2011" @default.
- W1510444590 type Work @default.
- W1510444590 sameAs 1510444590 @default.
- W1510444590 citedByCount "64" @default.
- W1510444590 countsByYear W15104445902012 @default.
- W1510444590 countsByYear W15104445902013 @default.
- W1510444590 countsByYear W15104445902014 @default.
- W1510444590 countsByYear W15104445902015 @default.
- W1510444590 countsByYear W15104445902016 @default.
- W1510444590 countsByYear W15104445902017 @default.
- W1510444590 countsByYear W15104445902018 @default.
- W1510444590 countsByYear W15104445902019 @default.
- W1510444590 countsByYear W15104445902020 @default.
- W1510444590 countsByYear W15104445902021 @default.
- W1510444590 countsByYear W15104445902022 @default.
- W1510444590 countsByYear W15104445902023 @default.
- W1510444590 crossrefType "journal-article" @default.
- W1510444590 hasAuthorship W1510444590A5042240287 @default.
- W1510444590 hasAuthorship W1510444590A5059944329 @default.
- W1510444590 hasBestOaLocation W15104445902 @default.
- W1510444590 hasConcept C104317684 @default.
- W1510444590 hasConcept C127716648 @default.
- W1510444590 hasConcept C170493617 @default.
- W1510444590 hasConcept C17991360 @default.
- W1510444590 hasConcept C203014093 @default.
- W1510444590 hasConcept C2775855021 @default.
- W1510444590 hasConcept C2776090121 @default.
- W1510444590 hasConcept C2778690821 @default.
- W1510444590 hasConcept C2779727006 @default.
- W1510444590 hasConcept C2908647359 @default.
- W1510444590 hasConcept C502942594 @default.
- W1510444590 hasConcept C51785407 @default.
- W1510444590 hasConcept C54355233 @default.
- W1510444590 hasConcept C71924100 @default.
- W1510444590 hasConcept C79484868 @default.
- W1510444590 hasConcept C86803240 @default.
- W1510444590 hasConcept C8891405 @default.