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• W1510604089 abstract "Aquaporins (AQPs) are membrane protein channels that allow the rapid passage of water through an epithelium containing tight junctions. In the present study, light microscope immunocytochemistry was utilized to localize several members of the AQP family in the testis, efferent ducts, and epididymis of normal adult animals during postnatal development and after various experimental procedures on adult animals. In the testis of normal adult animals, AQP-8 was expressed exclusively in Sertoli cells, while AQP-9 outlined Leydig cells. In the efferent ducts, AQP-1 was expressed on the microvilli, basolateral plasma membranes, and apical endosomes of the nonciliated cells and cilia of ciliated cells, while AQP-9 was present only on the microvilli of nonciliated cells. In the epididymis, AQP-9 was localized to the microvilli of the principal cells of all regions, with the most intense reaction being noted in the initial segment and cauda regions. The clear cells of the cauda region expressed only AQP-9. AQP-1 was not expressed in the testis or the epididymal epithelium, but it was expressed over the endothelial cells of the vascular channels of the efferent ducts and epididymis. After efferent duct ligation or orchidectomy, there was no change in the expression of AQP-1 or -9 over the microvilli or cilia of epithelial cells in the case of the efferent ducts, suggesting that testicular factors do not regulate their expression in this region. In contrast, AQP-9 expression in the principal cells of the initial segment, but not of other regions, and also in the clear cells of the cauda region was dramatically reduced after both treatments. As the expression was not restored to control levels by testosterone replacement, the data suggest that a luminal factor(s) derived from the testis regulates AQP-9 expression in the principal cells of the initial segment and in the clear cells of the cauda region. Postnatal studies revealed that the expression of AQP-1 and -9 in the different cell types of the efferent ducts and epididymis occurred between days 7 and 29, eliminating sperm and high androgen levels as possible regulating factors. Taken together, these data suggest cell specificity with respect to the expression of AQP-8 and -9 in the testis. In the efferent ducts and epididymis, specificity exists in cell, region, and tissue distribution with respect to the expression of AQP-1 and -9, and their expression does not appear to be regulated by androgens." @default.
• W1510604089 created "2016-06-24" @default.
• W1510604089 creator A5023085602 @default.
• W1510604089 creator A5080128878 @default.
• W1510604089 date "2002-05-11" @default.
• W1510604089 modified "2023-09-23" @default.
• W1510604089 title "Expression and regulation of aquaporins 1, 8, and 9 in the testis, efferent ducts, and epididymis of adult rats and during postnatal development." @default.
• W1510604089 cites W143470994 @default.
• W1510604089 cites W1483204570 @default.
• W1510604089 cites W1484846491 @default.
• W1510604089 cites W1492555480 @default.
• W1510604089 cites W1510979690 @default.
• W1510604089 cites W1513211408 @default.
• W1510604089 cites W1547137876 @default.
• W1510604089 cites W1834531680 @default.
• W1510604089 cites W1968378128 @default.
• W1510604089 cites W1969308673 @default.
• W1510604089 cites W1977203893 @default.
• W1510604089 cites W1988145915 @default.
• W1510604089 cites W1988357787 @default.
• W1510604089 cites W1989072962 @default.
• W1510604089 cites W1992814285 @default.
• W1510604089 cites W1994900003 @default.
• W1510604089 cites W2000162975 @default.
• W1510604089 cites W2003374038 @default.
• W1510604089 cites W2003485441 @default.
• W1510604089 cites W2003769012 @default.
• W1510604089 cites W2006437361 @default.
• W1510604089 cites W2006773599 @default.
• W1510604089 cites W2015004471 @default.
• W1510604089 cites W2016167081 @default.
• W1510604089 cites W2018551713 @default.
• W1510604089 cites W2020333525 @default.
• W1510604089 cites W2025148115 @default.
• W1510604089 cites W2027899259 @default.
• W1510604089 cites W2029084233 @default.
• W1510604089 cites W2030033462 @default.
• W1510604089 cites W2032554727 @default.
• W1510604089 cites W2037430544 @default.
• W1510604089 cites W2038942865 @default.
• W1510604089 cites W2040950777 @default.
• W1510604089 cites W2047348002 @default.
• W1510604089 cites W2055615962 @default.
• W1510604089 cites W2056594538 @default.
• W1510604089 cites W2058334508 @default.
• W1510604089 cites W2063181117 @default.
• W1510604089 cites W2064604600 @default.
• W1510604089 cites W2064775637 @default.
• W1510604089 cites W2072059146 @default.
• W1510604089 cites W2078961898 @default.
• W1510604089 cites W2080058556 @default.
• W1510604089 cites W2081687341 @default.
• W1510604089 cites W2093371144 @default.
• W1510604089 cites W2100898329 @default.
• W1510604089 cites W2104271112 @default.
• W1510604089 cites W2107113707 @default.
• W1510604089 cites W2109092035 @default.
• W1510604089 cites W2110431869 @default.
• W1510604089 cites W2119256636 @default.
• W1510604089 cites W2120215062 @default.
• W1510604089 cites W2121493816 @default.
• W1510604089 cites W2133280120 @default.
• W1510604089 cites W2136288803 @default.
• W1510604089 cites W2137168372 @default.
• W1510604089 cites W2140827018 @default.
• W1510604089 cites W2140934381 @default.
• W1510604089 cites W2141269411 @default.
• W1510604089 cites W2147059772 @default.
• W1510604089 cites W2154009044 @default.
• W1510604089 cites W2154312242 @default.
• W1510604089 cites W2158380695 @default.
• W1510604089 cites W2188895203 @default.
• W1510604089 cites W2199816912 @default.
• W1510604089 cites W2328412164 @default.
• W1510604089 cites W2403608084 @default.
• W1510604089 cites W2409420424 @default.
• W1510604089 cites W2423890419 @default.
• W1510604089 cites W3205694863 @default.
• W1510604089 cites W9121732 @default.
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